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Palmitoyl 3-carbacyclic phosphatidic acid 

目录号: HY-139061
产品使用指南

Palmitoyl 3-carbacyclic phosphatidic acid (HY-139061) 是棕榈酰化的 Carba 类环磷脂酸,是溶血磷脂酸 (LPA) 的类似物。Palmitoyl 3-carbacyclic phosphatidic acid 与 LPA 功能不同,能够抑制 RhoA 的激活,而抑制黑色素瘤细胞的迁移。在 B16-F0 异种移植小鼠模型中,Palmitoyl 3-carbacyclic phosphatidic acid 有效地抑制了实验性肺转移,减少了肿瘤结节的数量。

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Palmitoyl 3-carbacyclic phosphatidic acid Chemical Structure

Palmitoyl 3-carbacyclic phosphatidic acid Chemical Structure

CAS No. : 476310-22-2

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生物活性

Palmitoyl 3-carbacyclic phosphatidic acid (HY-139061) is a palmitoylated Carba-like cyclophosphatidic acid and an analog of lysophosphatidic acid (LPA). Palmitoyl 3-carbacyclic phosphatidic acid has different functions from LPA and can inhibit the activation of RhoA and inhibit the migration of melanoma cells. Palmitoyl 3-carbacyclic phosphatidic acid effectively inhibited experimental lung metastasis and reduced the number of tumor nodules in a B16-F0 xenograft mouse model[1].

分子量

390.49

Formula

C20H39O5P

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Palmitoyl 3-carbacyclic phosphatidic acid 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Palmitoyl 3-carbacyclic phosphatidic acid
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HY-139061
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