1. Anti-infection
  2. Bacterial Antibiotic
  3. Pefloxacin mesylate dihydrate

Pefloxacin mesylate dihydrate  (Synonyms: 甲磺酸培氟沙星二水合物; Pefloxacinium mesylate dihydrate)

目录号: HY-B0147B
产品使用指南

去水甲磺酸Pefloxacin是抗菌素,能通过抑制DNA旋转酶阻断细菌DNA复制。

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Pefloxacin mesylate dihydrate Chemical Structure

Pefloxacin mesylate dihydrate Chemical Structure

CAS No. : 149676-40-4

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Pefloxacin mesylate dihydrate 的其他形式现货产品:

Other Forms of Pefloxacin mesylate dihydrate:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pefloxacin mesylate dehydrate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections. Pefloxacin is commonly referred to as afluoroquinolone (or quinolone) drug and is a member of the fluoroquinolone class of antibacterials. It is an analog of norfloxacin. It is a synthetic fluoroquinolone, belonging to the 3rd generation of quinolones. Pefloxacin is extensively prescribed in France. Pefloxacin has not been approved for use in the United States. The bactericidal action of pefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited.

IC50 & Target

Quinolone

 

分子量

465.49

Formula

C18H28FN3O8S

CAS 号
中文名称

甲磺酸培氟沙星二水合物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Pefloxacin mesylate dihydrate 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pefloxacin mesylate dihydrate
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