1. Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  2. Apoptosis Reactive Oxygen Species
  3. Penduletin

Penduletin 是一种黄酮,可以从 Brickelia pendulaVitex negundo 中分离出来。Penduletin 显示出抗癌活性。Penduletin 通过 ROS 生成诱导癌细胞凋亡 (apoptosis)。

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Penduletin Chemical Structure

Penduletin Chemical Structure

CAS No. : 569-80-2

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规格 价格 是否有货 数量
1 mg ¥3420
1 周
5 mg ¥8730
1 周
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation[1][2].

体外研究
(In Vitro)

Penduletin(0-100 µg/mL,48 小时)对 HepG2 和 MCF-7 细胞系具有抗增殖活性,IC50 值分别为 25.8 和 6.4 µM[1]
Penduletin 可诱导 HepG2 中的 procaspase-3 裂解,以及 MCF-7 细胞系中的 procaspase-3 和 procaspase-8[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

344.32

Formula

C18H16O7

CAS 号
Unlabeled CAS

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Penduletin
目录号:
HY-N3096
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