2. Inhibitory Antibodies
  3. Pepinemab

Pepinemab  (Synonyms: VX 15/2503)

目录号: HY-P99407 纯度: 97.55%
COA

摩尔计算器

Pepinemab(VX 15/2503) 是一种人源化的抗 SEMA4D 单克隆抗体，信号蛋白 4D（SEMA4D），也称为 CD100，是神经元发育过程的调节子，在多种细胞过程中发挥作用。Pepinemab 可通过阻断 SEMA4D 的活性，用于阿尔茨海默病等多种神经退行性疾病研究。

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Pepinemab Chemical Structure

Pepinemab Chemical Structure

CAS No. : 2097151-87-4

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规格 价格 是否有货 数量
1 mg ￥2000
In-stock
5 mg ￥6000
In-stock
10 mg ￥9300
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Pepinemab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D[1].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Chimeric; Humanized
体外研究
(In Vitro)

Pepinemab(VX 15/2503)(48 h) 显著抑制原代人类星形细胞 CC-2565 中葡萄糖转运蛋白 (GLUT-1) 和单羧酸转运蛋白 (MCT)4 的表达，并抑制 SEMA4D 引起的星形细胞葡萄糖摄取的减少[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pepinemab 相关抗体:
Clinical Trial
CAS 号
Unlabeled Cas

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 97.55%

COA (172 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Pepinemab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pepinemab2097151-87-4VX 15/2503OthersSEMA4DCD100neuronal developmentAlzheimer's diseaseInhibitorinhibitorinhibit

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