1. GPCR/G Protein Metabolic Enzyme/Protease Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor
  2. Prostaglandin Receptor PPAR
  3. Prostaglandin A3

Prostaglandin A3  (Synonyms: PGA3)

目录号: HY-114822
产品使用指南

Prostaglandin A3 是前列腺素 E3 (PGE3) 的非酶脱水产物。Prostaglandin A3 对犬 EP2 和 EP4 受体表现出良好的亲和力,IC50 值分别为 120 和 20 nM。Prostaglandin A3 对人 PPARγKi 值为 188 μM。

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Prostaglandin A3 Chemical Structure

Prostaglandin A3 Chemical Structure

CAS No. : 36614-31-0

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  • 生物活性

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  • 参考文献

生物活性

Prostaglandin A3 is a non-enzymatic dehydration product of prostaglandin E3 (PGE3). Prostaglandin A3 showed good affinity for canine EP2 and EP4 receptors with IC50 values of 120 and 20 nM, respectively. The Ki value of Prostaglandin A3 for human PPARγ was 188 μM[1][2][3].

IC50 & Target

EP2

120 nM (IC50)

EP4

20 nM (IC50)

PPAR-γ

188 μM (Ki)

分子量

332.43

Formula

C20H28O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Prostaglandin A3
目录号:
HY-114822
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