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细胞分化

细胞分化是指多能性细胞(干细胞)逐渐发展为特定类型的细胞,具有特定结构和功能的过程。这是生物发育和组织形成的关键步骤,涉及基因表达调控和细胞命运决定。分化使细胞适应不同的组织和器官的特定需求,包括肌肉细胞、神经细胞等。研究细胞分化有助于理解生物体发育、组织修复和疾病发展,对干细胞治疗和再生医学等领域具有重要意义。


Cell differentiation refers to the process by which pluripotent cells (stem cells) gradually develop into specific types of cells with specific structures and functions. This is a critical step in biological development and tissue formation, involving gene expression regulation and cell fate decisions. Differentiation allows cells to adapt to the specific needs of different tissues and organs, including muscle cells, nerve cells, and more. Studying cell differentiation helps to understand organism development, tissue repair and disease development, and is of great significance to fields such as stem cell therapy and regenerative medicine.

相关实验方案

  • 细胞分化(cell differentiation)是指同一来源的细胞逐渐产生出形态结构、功能特征各不相同的细胞类群的过程。
  • 诱导多能干细胞 (Induced pluripotent stem cells,iPSCs) 是通过体细胞重编程得到类似胚胎干细胞特性的一种细胞类型。
  • 巨噬细胞是重要的免疫效应细胞,在固有免疫和适应性免疫应答中发挥重要作用。THP-1 细胞通常用佛波酯 (PMA) 诱导分化为巨噬细胞。