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基因本体论分析

基因本体论分析是一种用于解析基因功能和生物学过程的生物信息学方法。它利用基因本体(Gene Ontology,GO)数据库,将基因按照它们的分子功能、细胞组分和生物过程进行分类。通过基因本体论分析,可以揭示基因在生物体系中的功能和相互关系,有助于理解生物学的整体图景。常见的基因本体论分析工具包括DAVID、GOstat、GSEA等。这种方法广泛应用于基因表达分析、蛋白组学和系统生物学研究。


Gene ontology analysis is a bioinformatics method used to analyze gene functions and biological processes. It uses the Gene Ontology (GO) database to classify genes according to their molecular functions, cellular components and biological processes. Through gene ontology analysis, the functions and interrelationships of genes in biological systems can be revealed, which helps to understand the overall picture of biology. Common gene ontology analysis tools include DAVID, GOstat, GSEA, etc. This method is widely used in gene expression analysis, proteomics and systems biology research.