1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Pyruvate carboxylase

Pyruvate carboxylase 是一种含生物素的酶,可催化丙酮酸的 HCO3 和 MgATP 依赖性羧化形成草酰乙酸。Pyruvate carboxylase 通过调节肝脏糖异生、脂肪细胞脂肪酸合成以及胰腺 β 细胞胰岛素分泌,在控制全身能量方面发挥重要作用。

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Pyruvate carboxylase Chemical Structure

Pyruvate carboxylase Chemical Structure

CAS No. : 9014-19-1

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  • 生物活性

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生物活性

Pyruvate carboxylase is a biotin-containing enzyme that catalyzes the HCO3 and MgATP dependent carboxylation of pyruvate to form oxaloacetate. Pyruvate carboxylase plays an essential role in controlling whole-body energetics through regulation of gluconeogenesis in the liver, synthesis of fatty acids in adipocytes, and insulin secretion in pancreatic β cells[1][2].

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产品名称:
Pyruvate carboxylase
目录号:
HY-P2989
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