2. Others
  3. Isotope-Labeled Compounds
  4. Rapamycin-13C,d3

Rapamycin-13C,d3  (Synonyms: 雷帕霉素; 西罗莫司-13C,d3; Sirolimus-13C,d3; AY-22989-13C,d3)

目录号: HY-10219S1
产品使用指南

摩尔计算器

Rapamycin-13C,d3 (Sirolimus-13C,d3; AY-22989-13C,d3) 是 13C 和氘代标记的 Rapamycin (HY-10219) 的同位素。

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Rapamycin-<sup>13</sup>C,d<sub>3</sub> Chemical Structure

Rapamycin-13C,d3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

Other Forms of Rapamycin-13C,d3:

Rapamycin-13C,d3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rapamycin-13C,d3 (Sirolimus-13C,d3; AY-22989-13C,d3) is the 13C and deuterium labeled Rapamycin (HY-10219)[1]. Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[2]. Rapamycin is an autophagy activator, an immunosuppressant[3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Rapamycin-13C,d3 相关抗体:
分子量

918.18

Formula

C5013CH76D3NO13
Unlabeled Cas

53123-88-9
中文名称

雷帕霉素-13C,d3；西罗莫司-13C,d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rapamycin-13C,d3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rapamycin-13C,d3Sirolimus-13C,d3 AY-22989-13C,d3雷帕霉素-13C,d3西罗莫司-13C,d3Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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目录号：
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