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ACBD6 蛋白, Human (sf9, His)

目录号: HY-P76708
产品使用指南

ACBD6 蛋白选择性结合长链酰基辅酶 A,对不饱和 C18:1-CoA 显示出显着的偏好。与其他变体(例如不饱和 C20:4-CoA 和饱和 C16:0-CoA)不同,ACBD6 不与游离脂肪酸结合。在结构上,它作为单体存在,强调其单个单元的功能作用。这种特定的酰基辅酶 A 结合强调了 ACBD6 在与脂质代谢和涉及酰基辅酶 A 相互作用的细胞过程相关的复杂分子识别机制中的重要性。ACBD6 蛋白, Human (sf9, His) 是重组的 ACBD6 蛋白,由 Sf9 昆虫细胞表达,带有 N-His 标签。ACBD6 蛋白, Human (sf9, His) 全长 282 个氨基酸,分子量约为 ~36 kDa。

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描述

ACBD6 Protein selectively binds long-chain acyl-coenzyme A, displaying a notable preference for unsaturated C18:1-CoA. Unlike other variants such as unsaturated C20:4-CoA and saturated C16:0-CoA, ACBD6 does not bind to free fatty acids. Structurally, it exists as a monomer, emphasizing its individual unit's functional role. This specific acyl-coenzyme A binding underscores ACBD6's significance in intricate molecular recognition mechanisms related to lipid metabolism and cellular processes involving acyl-CoA interactions. ACBD6 Protein, Human (sf9, His) is the recombinant human-derived ACBD6 protein, expressed by Sf9 insect cells, with N-His labeled tag. The total length of ACBD6 Protein, Human (sf9, His) is 282 a.a., with molecular weight of ~36 kDa.

研究背景

ACBD6 蛋白通过选择性结合长链酰基辅酶 A 分子,在细胞代谢中发挥独特作用,与其他变体(例如不饱和 C20:4-CoA 和饱和 C16:0-)相比,ACBD6 蛋白对不饱和 C18:1-CoA 具有明显的偏好。辅酶A。重要的是,ACBD6 不表现出对游离脂肪酸的结合亲和力。在结构上,该蛋白质以单体形式存在,表明其功能活性与其单个单元相关,而不是与复杂的结构相关。酰基辅酶 A 结合的这种特异性强调了脂质代谢中涉及的复杂分子识别机制,突出了 ACBD6 在与酰基辅酶 A 相互作用相关的细胞过程中的作用。

种属

Human

表达系统

Sf9 insect cells

标签

N-His

蛋白编号

Q9BR61 (M1-A282)

基因 ID
蛋白结构
N-term
His
ACBD6 (M1-A282)
Accession # Q9BR61
C-term
同用名
Acyl-CoA-binding domain-containing protein 6; ACBD6
分子量

Approximately 36 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

ACBD6 Protein, Human (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ACBD6 Protein, Human (sf9, His)
目录号:
HY-P76708
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