2. 重组蛋白
  3. CD Antigens Complement System
  4. Platelet CD Proteins Erythrocyte CD Proteins Epithelial cell CD Proteins Endothelial cell CD Proteins Complement Regulatory Proteins
  5. DAF Protein/CD55 Decay Accelerating Factor (DAF)
  6. CD55/DAF 蛋白, Mouse (361a.a, HEK293, His)

CD55/DAF 蛋白, Mouse (361a.a, HEK293, His)

目录号: HY-P75655
COA 产品使用指南

CD55/DAF 蛋白在免疫系统中至关重要，可识别 C4b 和 C3b 片段。它与细胞相关的 C4b 和 C3b 相互作用，干扰它们的酶转化并阻止补体级联放大转化酶的形成。CD55/DAF 蛋白, Mouse (361a.a, HEK293, His) 是重组的 CD55/DAF 蛋白，由 HEK293 表达，带有 C-His 标签。CD55/DAF 蛋白, Mouse (361a.a, HEK293, His) 全长 361 个氨基酸，分子量约为 ~60 kDa。

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规格 价格 是否有货 数量
5 μg ￥950 In-stock
10 μg ￥1600 In-stock
20 μg ￥2500 In-stock
50 μg ￥4900 In-stock
100 μg   询价  

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描述

The CD55/DAF protein is critical in the immune system and recognizes C4b and C3b fragments. It interacts with cell-associated C4b and C3b, interfering with their enzymatic conversion and preventing the formation of complement cascade amplifying convertase. CD55/DAF Protein, Mouse (361a.a, HEK293, His) is the recombinant mouse-derived CD55/DAF protein, expressed by HEK293 , with C-His labeled tag. The total length of CD55/DAF Protein, Mouse (361a.a, HEK293, His) is 361 a.a., with molecular weight of ~60 kDa.
研究背景

CD55/DAF 蛋白通过识别 C4 和 C3 激活过程中产生的 C4b 和 C3b 片段，在免疫系统中发挥着至关重要的作用。它与细胞相关的 C4b 和 C3b 多肽的相互作用干扰它们催化 C2 和因子 B 转化为酶活性 C2a 和 Bb 的能力，从而阻止 C4b2a 和 C3bBb（补体级联的扩增转化酶）的形成。这种干扰作为一种调节机制，抑制补体激活并阻止 C3 和 C5 转化酶的形成，从而减轻补体诱导的损伤。CD55/DAF 识别和调节补体成分的能力强调了其在免疫调节和保护宿主细胞免受补体介导的伤害中的关键作用。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

Q61475 (M1-T361)
基因 ID

13136  [NCBI]
蛋白结构
N-term
DAF (M1-T361)
Accession # Q61475
His
C-term
同用名
Complement Decay-Accelerating factor; CD55; CR; DAF
氨基酸序列

MIRGRAPRTRPSPPPPLLPLLSLSLLLLSPTVRGDCGPPPDIPNARPILGRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWSSHETFCEKSCVAPERLSFASLKKEYLNMNFFPVGTIVEYECRPGFRKQPPLPGKATCLEDLVWSPVAQFCKKKSCPNPKDLDNGHINIPTGILFGSEINFSCNPGYRLVGVSSTFCSVTGNTVDWDDEFPVCTEIHCPEPPKINNGIMRGESDSYTYSQVVTYSCDKGFILVGNASIYCTVSKSDVGQWSSPPPRCIEKSKVPTKKPTINVPSTGTPSTPQKPTTESVPNPGDQPTPQKPSTVKVSATQHVPVTKTTVRHPIRTSTDKGEPNT

分子量

Approximately 60 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)

CD55/DAF Protein, Mouse (361a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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