2. 重组蛋白
  3. Immune Checkpoint Proteins CD Antigens
  4. Inhibitory Checkpoint Molecules NK Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins Cell Adhesion-related CD Proteins
  5. CD96
  6. CD96 蛋白, Cynomolgus (481a.a, HEK293, His)

CD96 蛋白, Cynomolgus (481a.a, HEK293, His)

目录号: HY-P700686
产品使用指南

CD96 蛋白是一种 I 型膜蛋白。该蛋白可能在免疫应答后期活化 T 细胞和 NK 细胞的粘附相互作用中发挥作用。它也可能在抗原呈递中起作用。CD155 作为 CD96 受体的主要配体。CD96 蛋白, Cynomolgus (481a.a, HEK293, His) 是重组的 CD96 蛋白，由 HEK293 表达，带有 C-His 标签。CD96 蛋白, Cynomolgus (481a.a, HEK293, His) 全长 481 个氨基酸，分子量为 80-130 kDa。

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3.  试用装只面向终端客户。

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描述

CD96 protein is a type I membrane protein. This protein may play a role in the adhesion interaction between activated T cells and NK cells in the late stage of immune response. It may also play a role in antigen presentation. CD155 acts as the main ligand of the CD96 receptor. CD96 Protein, Cynomolgus (481a.a, HEK293, His) is the recombinant cynomolgus-derived CD96 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD96 Protein, Cynomolgus (481a.a, HEK293, His) is 481 a.a., with molecular weight of 80-130 kDa.
研究背景

CD96 基因编码的蛋白质属于免疫球蛋白超家族。它是一种 I 型膜蛋白。该蛋白可能在免疫应答后期活化 T 细胞和 NK 细胞的粘附相互作用中发挥作用。它也可能在抗原呈递中起作用。CD155 作为 CD96 受体的主要配体。CD96 介导 NK 细胞与表达髓样病毒受体 (myeloid virus receptor, PVR)/CD155 的细胞的粘附，促进它们的相互作用，从而刺激 NK 细胞的细胞毒活性。CD96 的这种前粘附特性和 PVR 在某些肿瘤中的高表达有助于 NK 细胞对肿瘤的识别和肿瘤细胞的死亡。
种属

Cynomolgus
表达系统

HEK293
标签

C-His
蛋白编号

A0A2K5TWV6 (V22-G502)
基因 ID

102121080
蛋白结构
N-term
CD96 (V22-G502)
Accession # A0A2K5TWV6
His
C-term
同用名
CD96 molecule; CD96; DKFZp667E2122; TACTILE
分子量

80-130 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CD96 Protein, Cynomolgus (481a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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