1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Stem Cell CD Proteins Cell Adhesion Molecules (CAMs)
  4. NCA-95/CD66b Immunoglobulin-like Cell Adhesion Molecules
  5. CEA Cell Adhesion Molecule 8/NCA-95
  6. CEACAM8/CD66b 蛋白, Human (HEK293, His)

CEACAM8/CD66b 蛋白, Human (HEK293, His)

目录号: HY-P72692
产品使用指南

CEACAM8/CD66b蛋白是一种细胞表面糖蛋白,可促进钙非依赖性异嗜细胞与其他癌胚抗原相关细胞粘附分子的粘附,特别是CEACAM6,在活化的中性粒细胞中尤其明显。CEACAM8/CD66b 蛋白, Human (HEK293, His) 是重组的 CEACAM8/CD66b 蛋白,由 HEK293 表达,带有 C-6*His 标签。CEACAM8/CD66b 蛋白, Human (HEK293, His) 全长 107 个氨基酸,分子量为 17-25 kDa。

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描述

CEACAM8/CD66b protein is a cell surface glycoprotein that promotes calcium-independent heterophil cell adhesion to other carcinoembryonic antigen-related cell adhesion molecules, particularly CEACAM6, in activated neutrophils Especially obvious. CEACAM8/CD66b Protein, Human (HEK293, His) is the recombinant human-derived CEACAM8/CD66b protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CEACAM8/CD66b Protein, Human (HEK293, His) is 107 a.a., with molecular weight of 17-25 kDa.

研究背景

CEACAM8/CD66b 蛋白是一种细胞表面糖蛋白,以不依赖钙的方式积极促进细胞粘附。它主要介导异嗜性细胞粘附,与其他癌胚抗原相关细胞粘附分子(包括 CEACAM6)形成相互作用。值得注意的是,与 CEACAM8 的异嗜性相互作用专门发生在活化的中性粒细胞中。CEACAM8 作为单体运行,也与 CEACAM6 形成异二聚体,通过其 Ig 样 V 型结构域参与异二聚化。这强调了它作为多功能细胞粘附分子的作用,参与与各种伙伴的相互作用,并强调了它在不同细胞环境中的重要性,特别是在活化的中性粒细胞中以及在与其他 CEACAM 家族成员的异嗜性粘附过程中。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

P31997 (Q35-H141)

基因 ID
蛋白结构
N-term
CEACAM8 (Q35-H141)
Accession # P31997
6*His
C-term
同用名
Carcinoembryonic antigen-related cell adhesion molecule 8; CD67; CD66b; CEACAM8; CGM6
氨基酸序列

QLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVH

分子量

17-25 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CEACAM8/CD66b Protein, Human (HEK293, His)
目录号:
HY-P72692
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