1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Peptide Hormone & Neuropeptides
  4. CG-alpha
  5. CG alpha 蛋白, Human (HEK293, mFc)

CG alpha 蛋白, Human (HEK293, mFc)

目录号: HY-P75341
产品使用指南

CG α 蛋白是糖蛋白激素(TSH、LH、FSH、CG)中的共享 α 链,与受体结合,启动信号传导通路。异二聚体激素涉及 CG α 和特定的 β 链(TSHB、LHB、FSHB、CGB),从而赋予生物特异性。CG alpha 蛋白, Human (HEK293, mFc) 是重组的 CG α 蛋白,由 HEK293 表达,带有 C-mFc 标签。CG alpha 蛋白, Human (HEK293, mFc) 全长 92 个氨基酸,分子量约为 ~45.8 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

The CG alpha protein, a shared alpha chain in glycoprotein hormones (TSH, LH, FSH, CG), binds to receptors, initiating signaling pathways. Heterodimeric hormones involve CG alpha and a specific beta chain (TSHB, LHB, FSHB, CGB), imparting biological specificity. CG alpha Protein, Human (HEK293, mFc) is the recombinant human-derived CG alpha protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CG alpha Protein, Human (HEK293, mFc) is 92 a.a., with molecular weight of ~45.8 kDa.

研究背景

CG α 蛋白作为活性异二聚体糖蛋白激素中的共享 α 链,包括促甲状腺素 (TSH)、促黄体激素 (LH)、促卵泡素 (FSH) 和绒毛膜促性腺激素 (CG)。这些激素与靶细胞上的特定受体结合,启动下游信号通路。这些激素的异二聚体结构涉及 CG α 链(如此处所述)和独特的 β 链,该链赋予每种激素生物特异性。具体地,TSH由CGα和TSHβ(TSHB)组成,促卵泡素由CGα和LHβ(LHB)组成,促卵泡素包括CGα和FSHβ(FSHB),绒毛膜促性腺激素由CGα和绒毛膜促性腺激素亚基β(CGB)组成。。

种属

Human

表达系统

HEK293

标签

C-mFc

蛋白编号

P01215 (A25-S116)

基因 ID
蛋白结构
N-term
CG alpha (A25-S116)
Accession # P01215
mFc
C-term
同用名
Glycoprotein hormones alpha chain; CG-alpha; FSH-alpha; CGA
分子量

Approximately 45.8 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CG alpha Protein, Human (HEK293, mFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CG alpha Protein, Human (HEK293, mFc)
目录号:
HY-P75341
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