2. 重组蛋白
  3. CAR-T related Proteins Receptor Proteins Fluorescent-labeled Recombinant Proteins
  4. Folate Receptor alpha (FR-alpha)
  5. FITC-Labeled FOLR1 蛋白, Human (HEK293, His)

FITC-Labeled FOLR1 蛋白, Human (HEK293, His)

目录号: HY-P701278
产品使用指南

FOLR1 蛋白是叶酸摄取的重要介质，与叶酸结合并促进 5-甲基四氢叶酸输送到细胞中。研究表明在中性 pH 值下具有高亲和力。FITC-Labeled FOLR1 蛋白, Human (HEK293, His) 是重组的 FITC 标记的 FOLR1 蛋白，由 HEK293 表达，带有 His 标签。FITC-Labeled FOLR1 蛋白, Human (HEK293, His) 全长 209 个氨基酸，分子量为 35-43 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

The FOLR1 protein is an important mediator of folate uptake, binding to folate and promoting the delivery of 5-methyltetrahydrofolate into cells. Studies show high affinity at neutral pH. FITC-Labeled FOLR1 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled FOLR1 protein, expressed by HEK293 , with His labeled tag. The total length of FITC-Labeled FOLR1 Protein, Human (HEK293, His) is 209 a.a., with molecular weight of 35-43 kDa.
研究背景

FOLR1 蛋白作为叶酸摄取的关键介质，与叶酸和还原叶酸衍生物结合，促进 5-甲基四氢叶酸和叶酸类似物输送到细胞内部。各种研究证明，该过程的特点是在中性 pH 值下对叶酸和叶酸类似物具有高亲和力。值得注意的是，受体内吞作用后暴露于弱酸性 pH 值会引起构象变化，显着降低其对叶酸的亲和力，促进其释放。除了在叶酸转运中的作用之外，FOLR1 对于正常胚胎发育和适当的细胞增殖至关重要，强调了其在基本细胞过程中的重要性。
种属

Human
表达系统

HEK293
标签

His
蛋白编号

P15328 (R25-M233)
基因 ID

2348
同用名
FOLR-1; FBP; FOLR; FRα
分子量

35-43 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

FITC-Labeled FOLR1 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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