GMPR 蛋白, Human (His)

GMPR protein plays a crucial role in nucleotide metabolism by catalyzing the irreversible NADPH-dependent deamination of to IMP. This enzymatic activity is pivotal for the conversion of nucleobase, nucleoside, and nucleotide derivatives of guanine (G) to adenine (A) nucleotides, contributing to the intricate network of biochemical processes involved in maintaining the essential intracellular balance between A and G nucleotides. GMPR Protein, Human (His) is the recombinant human-derived GMPR protein, expressed by E. coli , with N-His labeled tag. The total length of GMPR Protein, Human (His) is 345 a.a., with molecular weight of ~37 kDa.

GMPR 蛋白通过催化 GMP 到 IMP 的不可逆 NADPH 依赖性脱氨基作用，在核苷酸代谢中发挥着至关重要的作用。这种酶活性对于鸟嘌呤 (G) 的核碱基、核苷和核苷酸衍生物转化为腺嘌呤 (A) 核苷酸至关重要，有助于维持 A 和 G 核苷酸之间基本的细胞内平衡所涉及的生化过程的复杂网络。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-His

P36959 (M1-S345)

2766  [NCBI]

Approximately 37 kDa

Greater than 85% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 40% Glycerol, 1 mM DTT, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.