1. 重组蛋白
  2. Others
  3. KCNJ16 蛋白, Rat (Cell-Free, His)

KCNJ16 蛋白, Rat (Cell-Free, His)

目录号: HY-P702346
产品使用指南

KCNJ16 是内向整流钾通道的成员,促进钾内流并受细胞外钾浓度调节。其向内整流涉及内部镁对向外电流的抑制。KCNJ16 蛋白, Rat (Cell-Free, His) 是重组的 KCNJ16 蛋白,由 E. coli Cell-free 表达,带有 N-10*His 标签。KCNJ16 蛋白, Rat (Cell-Free, His) 全长 419 个氨基酸,分子量为 54.0 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

KCNJ16 is a member of the inwardly rectifying potassium channel, which facilitates potassium influx and is regulated by extracellular potassium concentration. Its inward rectification involves the suppression of outward current by internal magnesium. KCNJ16 Protein, Rat (Cell-Free, His) is the recombinant rat-derived KCNJ16 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of KCNJ16 Protein, Rat (Cell-Free, His) is 419 a.a., with molecular weight of 54.0 kDa.

研究背景

KCNJ16 是内向整流钾通道的成员,表现出偏好允许钾流入而不是流出,其电压敏感性受细胞外钾浓度调节。通道的内向整流主要归因于内部镁对外向电流的抑制。从功能上讲,KCNJ16 参与体液和 pH 平衡的调节。特别是在肾脏中,KCNJ16 与 KCNJ10 结合可促进远端肾小管的基底外侧 K(+) 循环,这是这些肾小管中 Na(+) 重吸收的关键过程。作为 KCNJ10 的异二聚体,KCNJ16 与 MAGI1 形成重要的相互作用,可能有助于肾细胞基底外侧膜钾通道的表达。此外,KCNJ16 可能与 Kir2.1/KCNJ2 发生异二聚化,从而扩展其在细胞膜内的功能关联。

种属

Rat

表达系统

E. coli Cell-free

标签

N-10*His

蛋白编号

P52191 (M1-M419)

基因 ID

/

蛋白结构
N-term
10*His
KCNJ16 (M1-M419)
Accession # P52191
C-term
同用名
Inward rectifier potassium channel 16; BIR9; Inward rectifier K(+) channel Kir5.1; Potassium channel, inwardly rectifying subfamily J member 16
氨基酸序列

MSYYGSSYRIVNVDSKYPGYPPEHAIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYMVDIFTTLVDTKWRHMFVVFSLSYILSWLIFGSIFWLIALHHGDLLSDPDITPCVDNVHSFTAAFLFSLETQTTIGYGYRCVTEECSVAVLTVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYSEDSEGRMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFHDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLNNLEKTSPARGSCTSDTNTRRRSFSAVAMVSSCENPEETSLSPQDECKEVPYQKALLTLNRISMESQM

分子量

54.0 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

KCNJ16 Protein, Rat (Cell-Free, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
KCNJ16 Protein, Rat (Cell-Free, His)
目录号:
HY-P702346
需求量: