2. 重组蛋白
  3. Others
  4. NME1/NDPKA 蛋白, Human (His)

NME1/NDPKA 蛋白, Human (His)

目录号: HY-P70299
产品使用指南

NME1/NDPKA 蛋白在三磷酸核苷的合成中起着至关重要的作用，并表现出多种活性，包括核苷二磷酸激酶、丝氨酸/苏氨酸特异性蛋白激酶、香叶基和法尼基焦磷酸激酶、组氨酸蛋白激酶和 3'-5' 核酸外切酶功能。NME1/NDPKA 蛋白, Human (His) 是重组的 NME1/NDPKA 蛋白，由 E. coli 表达，带有 N-6*His 标签。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The NME1/NDPKA protein plays a crucial role in the synthesis of nucleoside triphosphates and exhibits multiple activities, including nucleoside diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease functions. NME1/NDPKA Protein, Human (His) is the recombinant human-derived NME1/NDPKA protein, expressed by E. coli , with N-6*His labeled tag.
研究背景

NME1/NDPKA 蛋白在合成三磷酸核苷（ATP 除外）中起主要作用。它利用乒乓机制，通过磷酸化活性位点中间体将 ATP γ 磷酸转移到 NDP β 磷酸。该蛋白质表现出多种活性，包括核苷二磷酸激酶、丝氨酸/苏氨酸特异性蛋白激酶、香叶基/法呢基焦磷酸激酶、组氨酸蛋白激酶和3'-5'核酸外切酶。NME1 对于细胞增殖、分化、发育、信号转导、G 蛋白偶联受体内吞作用和基因表达至关重要。它对于神经发育至关重要，影响神经模式和细胞命运的决定。在 GZMA 介导的细胞死亡中，NME1 与 TREX1 合作，在一条 DNA 链上产生切口并增强 DNA 损伤，以防止快速修复和重新退火。
种属

Human
表达系统

E. coli
标签

N-6*His
蛋白编号

P15531-1 (M1-E152)
基因 ID
蛋白结构
N-term
6*His
NME1 (M1-E152)
Accession # P15531-1
C-term
同用名
rHuNucleoside diphosphate kinase A/NDPKA, His; Nucleoside Diphosphate Kinase A; NDK A; NDP Kinase A; Granzyme A-Activated DNase; GAAD; Metastasis Inhibition Factor nm23; Tumor Metastatic Process-Associated Protein; nm23-H1; NME1; NDPKA; NM23
氨基酸序列

MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE

分子量

Approximately 20.0 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

NME1/NDPKA Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
NME1/NDPKA Protein, Human (His)
目录号：
HY-P70299
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z