RAB6A 蛋白, Human (His)

RAB6A protein forms a complex with BICD1 and directly interacts with DYNLRB1 in the GDP-bound state, suggesting a regulatory role in coordinating cellular functions. In the GTP-bound state, RAB6A interacts with VPS13B, suggesting involvement in VPS13B-related pathways. RAB6A Protein, Human (His) is the recombinant human-derived RAB6A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB6A Protein, Human (His) is 208 a.a., with molecular weight of ~26 kDa.

研究证明，RAB6A 蛋白参与细胞过程中的特定相互作用，与 BICD1 形成复合物。此外，RAB6A 在其 GDP 结合状态下表现出与 DYNLRB1 的直接相互作用。这种相互作用表明 RAB6A 在协调与 DYNLRB1 相关的细胞功能中发挥调节作用。此外，在 GTP 结合状态下，RAB6A 与 VPS13B 相互作用，表明其参与与 VPS13B 相关的分子途径。这些相互作用凸显了 RAB6A 在调节各种细胞过程中的多功能性，并强调需要进一步探索以揭示这些关联背后的具体作用和调节机制。

Human

E. coli

N-His

P20340-2 (M1-C208)

5870  [NCBI]

MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC

Approximately 26 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.