SCGB3A2 蛋白, Mouse (His, GST)

SCGB3A2 is a secreted cytokine-like protein that interacts with pathogens (Listeria monocytogenes, Pseudomonas aeruginosa, yeast) and binds to the scavenger receptor MARCO. It strongly inhibits PLA2G1B activity and regulates lipid metabolism. SCGB3A2 Protein, Mouse (His, GST) is the recombinant mouse-derived SCGB3A2 protein, expressed by E. coli , with N-GST, N-6*His labeled tag. The total length of SCGB3A2 Protein, Mouse (His, GST) is 118 a.a., with molecular weight of ~43.2 kDa.

SCGB3A2 是一种分泌的细胞因子样蛋白，具有多种功能，包括与清道夫受体 MARCO 结合以及与各种病原体（例如革兰氏阳性菌单核细胞增多性李斯特菌、革兰氏阴性菌铜绿假单胞菌和酵母）相互作用。值得注意的是，它强烈抑制磷脂酶 A2 (PLA2G1B) 活性，显示其在脂质代谢中的调节作用。SCGB3A2 在呼吸道上皮细胞中具有抗炎作用，并在肺部发挥抗纤维化活性。它可能有助于胎儿肺的发育和成熟，促进肺发育早期阶段的分支形态发生。此外，在垂体中，SCGB3A2 还参与抑制卵泡刺激素 (FSH) 和黄体生成素 (LH) 的产生。该蛋白质以同二聚体形式存在，通过二硫键连接，也可以作为单体发挥作用。此外，SCGB3A2 与 APOA1 相互作用，强调其参与多种生理过程。

Mouse

E. coli

N-GST;N-6*His

Q920H1 (L22-L139)

117158  [NCBI]

LLINRLPVVDKLPVPLDDIIPSFDPLKMLLKTLGISVEHLVTGLKKCVDELGPEASEAVKKLLVIIICSYFPGRSLCYVNNLPSFVSVLFLPMICAYPRDSKKQTFAFIERVFEQSKL

Approximately 43.2 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.