Semaphorin-4D/SEMA4D 蛋白, Rat (HEK293, Fc)

Semaphorin-4D (SEMA4D) is predicted to participate in the same protein binding, signaling receptor binding, and transmembrane signaling receptor activities. Its multiple roles, including negative regulation of osteoblast differentiation and modulation of neuronal projection development, highlight its functional versatility. Semaphorin-4D/SEMA4D Protein, Rat (HEK293, Fc) is the recombinant rat-derived Semaphorin-4D/SEMA4D protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Semaphorin-4D/SEMA4D Protein, Rat (HEK293, Fc) is 712 a.a., with molecular weight of ~118 kDa.

Semaphorin-4D (SEMA4D) 预计具有相同的蛋白质结合活性、信号传导受体结合活性和跨膜信号传导受体活性。它参与多种过程，包括成骨细胞分化的负调节、神经元投射发育的调节和磷酸盐代谢过程的调节，强调了其多种功能。SEMA4D 预计在轴突发生的正向调节上游或内部发挥作用，表明在神经元发育中发挥作用。细胞外空间的预测活动及其作为质膜组成部分的地位进一步强调了其在细胞间通讯中的潜在重要性。由于在脾脏、胸腺和其他九种组织等组织中观察到了偏向表达，SEMA4D 在细胞过程中的复杂参与及其对组织特异性功能的潜在影响成为进一步探索的兴趣领域。

Rat

HEK293

C-hFc

NP_001164034 (M1-M712)

306790  [NCBI]

Approximately 118 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.