TNFRSF12A 蛋白, Human (HEK293, Fc)

TNFRSF12A Protein, the receptor for TNFSF12/TWEAK, acts as a weak apoptosis inducer in specific cell types. It also promotes angiogenesis, endothelial cell proliferation, and may modulate cellular adhesion to matrix proteins. Association with TRAF1, TRAF2, and potentially TRAF3 underscores its involvement in diverse cellular signaling pathways. TNFRSF12A Protein, Human (HEK293, Fc) is the recombinant human-derived TNFRSF12A protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TNFRSF12A Protein, Human (HEK293, Fc) is 52 a.a., with molecular weight of 30-40 kDa.

TNFRSF12A 蛋白充当 TNFSF12/TWEAK 的受体，并且在某些细胞类型中充当细胞凋亡的弱诱导剂。此外，它在促进血管生成和内皮细胞增殖方面发挥作用，并且可以调节细胞对基质蛋白的粘附。该蛋白与 TRAF1 和 TRAF2 相关，并且可能与 TRAF3 相关，表明它参与多种细胞信号传导途径。

Human

HEK293

C-hFc

Q9NP84 (E28-W79)

51330  [NCBI]

EQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAAPPAPFRLLW

30-40 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.