1. 重组蛋白
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. TSSK4 蛋白, Human (Sf9, GST)

TSSK4 蛋白, Human (Sf9, GST)

目录号: HY-P701652
产品使用指南

TSSK4 蛋白是一种关键的丝氨酸/苏氨酸激酶,对于男性生殖细胞发育至关重要,并有助于成熟精子的功能。它可能参与 Cre/Creb 信号通路,磷酸化“Ser-133”上的 CREB1 并刺激该通路。TSSK4 蛋白, Human (Sf9, GST) 是重组的 TSSK4 蛋白,由 Sf9 insect cells 表达,带GST标签。TSSK4 蛋白, Human (Sf9, GST) 全长 327 个氨基酸。

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描述

The TSSK4 protein is a critical serine/threonine kinase that is essential for male germ cell development and contributes to mature sperm function. It may participate in the Cre/Creb signaling pathway, phosphorylate CREB1 on "Ser-133" and stimulate this pathway. TSSK4 Protein, Human (Sf9, GST) is the recombinant human-derived TSSK4 protein, expressed by Sf9 insect cells , with GST tagged. The total length of TSSK4 Protein, Human (Sf9, GST) is 327 a.a., .

研究背景

TSSK4 是一种丝氨酸/苏氨酸激酶,在男性生殖细胞发育中发挥着关键作用,并有助于成熟的精子功能。它可能参与 Cre/Creb 信号通路,因为它能够在体外磷酸化“Ser-133”上的 CREB1 并刺激细胞中的 Cre/Creb 通路。此外,TSSK4 在体外对 CREM 'Ser-116' 处表现出磷酸化活性。TSSK4 磷酸化的另一个目标是 ODF2,其中“Ser-95”是特定的磷酸化位点。这些发现强调了 TSSK4 在与男性生殖细胞发育和精子功能相关的关键细胞过程中的多方面参与。

种属

Human

表达系统

Sf9 insect cells

标签

GST

蛋白编号

Q6SA08 (G2-T328)

基因 ID

283629

同用名
TSSK4; Testis-specific serine/threonine-protein kinase 4; TSK-4; TSSK-4; Testis-specific kinase 4; Serine/threonine-protein kinase 22E
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TSSK4 Protein, Human (Sf9, GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TSSK4 Protein, Human (Sf9, GST)
目录号:
HY-P701652
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