1. Cell Cycle/DNA Damage Epigenetics
  2. Sirtuin
  3. SIRT3 activator 1

SIRT3 activator 1 (Compound 5v) 是一种 SIRT3 激活剂。SIRT3 activator 1 选择性升高 SIRT3 表达,导致 SOD2 和 OPA1 表达上调,有效预防线粒体功能障碍,减轻氧化应激,保持心肌细胞活力。SIRT3 activator 1 可用于心血管疾病的研究。

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SIRT3 activator 1 Chemical Structure

SIRT3 activator 1 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SIRT3 activator 1 (Compound 5v) is a SIRT3 activator. SIRT3 activator 1 selectively elevates SIRT3 expression, leading to the upregulation of SOD2 and OPA1 expression, effectively preventing mitochondrial dysfunction, mitigating oxidative stress, and preserving cardiomyocyte viability. SIRT3 activator 1 can be used for research of cardiovascular diseases[1].

体外研究
(In Vitro)

SIRT3 activator 1 (0-10 μM) 通过激活 SIRT3/SOD2 和 OPA1 通路保护心肌细胞免受 H9c2 细胞中 Doxorubicin (HY-15142A) 诱导的氧化损伤[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

556.67

Formula

C32H41N2NaO5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

SIRT3 activator 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SIRT3 activator 1
目录号:
HY-158162
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