2. Anti-infection
  3. Bacterial
  4. T3SS-IN-5

T3SS-IN-5 (Compound F9) 是毒力因子中的第三型分泌系统 （T3SS） 的特异性抑制剂。T3SS-IN-5 通过抑制 T3SS 相关基因的表达，来减少细菌的致病性而不影响细菌的生存能力。

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T3SS-IN-5 Chemical Structure

T3SS-IN-5 Chemical Structure

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T3SS-IN-5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

T3SS-IN-5 (Compound F9) is a specific inhibitor of the type III secretion system (T3SS). T3SS-IN-5 reduces bacterial pathogenicity without affecting bacterial viability by inhibiting the expression of genes associated with T3SS[1].

体外研究
(In Vitro)

T3SS-IN-5 对 Xcc 的生存能力没有统计学上的显著影响[1]。
T3SS-IN-5 (200 μM; 5 d) 使 Xcc-jx-6 诱导的 本氏烟草的过敏反应 (HR) 显著降低[1]。
T3SS-IN-5 (200 μM; 4-7 d) 减轻了奥拉赫橙的溃疡症状，在同等浓度下效果比 bismerthiazol 更明显[1]。
T3SS-IN-5 (200 μM; 16 h) 处理后，Xcc 的相对发病率显著降低[1]。
T3SS-IN-5 (200 μM; 48 h-5 d) 不影响 Xcc 其他毒力因子，包括胞外酶活性、EPS活性、运动性和生物膜形成[1]。
T3SS-IN-5 (100-200 μM; 4 d) 和 Burkholderia anthina hN-8 联合使用进一步改善了对 Xcc 的抑制作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

T3SS-IN-5 相关抗体:

RT-PCR[1]

Cell Line: hrp cluster
Concentration: 200 μM
Incubation Time: 16 h
Result: Significantly reduced the expression levels of key T3SS genes (hrpG, hrpX, hrpE, hrcC, hrcT, and hpa1) in the Xcc.
Significantly reduced the expression of the critical disease susceptibility gene, Citrus sinensis lateral organ boundary 1 (CsLOB1).
分子量

314.43

Formula

C16H14N2OS2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

T3SS-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

T3SS-IN-5Bacterialcitrus cankerXanthomonas citri subsp. citri (Xcc)type III secretion system (T3SS)mandelic acid derivativesquorum quenchingInhibitorinhibitorinhibit

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目录号：
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