2. PI3K/Akt/mTOR Apoptosis
  3. Akt Apoptosis
  4. TCL1(10-24)

TCL1(10-24) 是人类 TCL1 的 betaA 链。TCL1(10-24) 是一种 Akt 抑制剂，与 Akt PH 结构域相互作用，阻止磷酸肌醇结合，从而抑制 Akt 的膜易位和激活。TCL1(10-24) 抑制细胞增殖和抗凋亡，在体内具有肿瘤生长作用。

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TCL1(10-24) Chemical Structure

TCL1(10-24) Chemical Structure

CAS No. : 835655-37-3

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TCL1(10-24) 相关抗体

Top Publications Citing Use of Products

查看 Akt 亚型特异性产品:

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Akt Akt1 Akt2 Akt3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TCL1(10-24) is a encompassing the betaA strand of human TCL1. TCL1(10-24) is a Akt inhibitor. TCL1(10-24) interacts with the Akt PH domain prevented phosphoinositide binding and hence inhibits membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis. TCL1(10-24) has tumor growth in vivo[1].

分子量

1871.06

Formula

C88H123N23O23
CAS 号
Unlabeled CAS

Sequence

Ala-Val-Thr-Asp-His-Pro-Asp-Arg-Leu-Trp-Ala-Trp-Glu-Lys-Phe
Sequence Shortening

AVTDHPDRLWAWEKF
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TCL1(10-24) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TCL1(10-24)835655-37-3AktApoptosisPKBProtein kinase BbetaA strandTCL1PH domainphosphoinositidemembrane translocationproliferationtumorInhibitorinhibitorinhibit

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目录号：
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