1. Immunology/Inflammation
  2. Complement System
  3. Tesidolumab

Tesidolumab  (Synonyms: LFG316; Anti-Human C5 Recombinant Antibody)

目录号: HY-P99322 纯度: 97.01%
COA

Tesidolumab (LFG316) 是一种全人IgG1/λ抗c5单克隆抗体,分子量为143 kDa(不含糖基化)。Tesidolumab (LFG316)阻断C5的切割,防止膜攻击复合体的后续形成。

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Tesidolumab Chemical Structure

Tesidolumab Chemical Structure

CAS No. : 1531594-08-7

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规格 价格 是否有货 数量
1 mg ¥2000
In-stock
5 mg ¥5800
In-stock
10 mg ¥8990
In-stock
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100 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex[1].

同型

Human IgG1 lambda1

推荐同型对照抗体
种属

Human

体外研究
(In Vitro)

Tesidolumab (LFG316) possesses a half-life in humans of approximately 9 days. Tesidolumab (LFG316) binds to a distinct epitope to that of eculizumab and ravulizumab, distant to Arg 885[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
Unlabeled Cas

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

纯度: 97.01%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tesidolumab
目录号:
HY-P99322
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