2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Sigma Receptor Potassium Channel iGluR
  4. threo-Ifenprodil hemitartrate

threo-Ifenprodil hemitartrate 

目录号: HY-107708
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摩尔计算器

threo Ifenprodil hemitartrate 是一种 σ 受体激动剂，σ1 和 σ2 受体的 Kis 分别为 59.1 和 2 nM。threo Ifenprodil hemitartrate 也是一种 NR2B 亚基选择性的 NMDA 受体拮抗剂 (IC50=0.22 μM)。threo Ifenprodil hemitartrate 还可有效抑制 hERG 钾通道，其 IC 50 值为 88 nM，具有抗心律失常活性。

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threo-Ifenprodil hemitartrate Chemical Structure

threo-Ifenprodil hemitartrate Chemical Structure

CAS No. : 1312991-83-5

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threo-Ifenprodil hemitartrate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

threo Ifenprodil hemitartrate is a σ receptor agonist, with Kis of 59.1 and 2 nM for σ1 and σ2 receptors, respectively. threo Ifenprodil hemitartrate is also a NR2B subunit-selective NMDA receptor antagonist (IC50=0.22 μM). threo Ifenprodil hemitartrate is a hERG potassium channel inhibitor, with an IC 50 of 88 nM, showing antiarrhythmic activity[1][2][3].

IC50 & Target

IC50: 0.22 μM (NMDA)[1].
分子量

400.50

Formula

C21H27NO2.1/2C4H6O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

threo-Ifenprodil hemitartrate 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

threo-Ifenprodil hemitartrate1312991-83-5Sigma ReceptorPotassium ChanneliGluRKcsAIonotropic glutamate receptorsInhibitorinhibitorinhibit

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