2. Inhibitory Antibodies
  3. Trabikibart

Trabikibart  (Synonyms: CSL311)

目录号: HY-P990094

摩尔计算器

Trabikibart (CSL311) 是一种 βc 特异性、全人单克隆抗体，可与人 βc 受体细胞因子结合位点特异性的独特表位结合，对人类 βc 受体具有皮摩尔结合亲和力。Trabikibart 是 IL-3、GM-CSF 和 IL-5 对嗜酸性粒细胞存活的联合作用的有效抑制剂。Trabikibart 具有用于慢性炎症性疾病的潜力。

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Trabikibart Chemical Structure

Trabikibart Chemical Structure

CAS No. : 2643974-98-3

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Trabikibart 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trabikibart (CSL311), a βc-specific, fully human monoclonal antibody, binds to a unique epitope that is specific to the cytokine-binding site of the human βc receptor. Trabikibart has picomolar binding affinity for the human βc receptor. Trabikibart is a potent inhibitor of the combined effects of IL-3, GM-CSF and IL-5 on the survival of eosinophils. Trabikibart has the potential for chronic inflammatory diseases research[1].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Human
CAS 号
Unlabeled CAS

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Trabikibart 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trabikibart2643974-98-3CSL311CSL 311CSL-311OthersβcIL-3GM-CSFIL-5eosinophilschronic inflammatoryInhibitorinhibitorinhibit

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