1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Tubulin inhibitor 31

Tubulin inhibitor 31 是一种有效的微管蛋白抑制剂,IC50 值为 4 µM。Tubulin inhibitor 31 显示出抗增殖活性。Tubulin inhibitor 31 抑制 HUVEC 的迁移。

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Tubulin inhibitor 31 Chemical Structure

Tubulin inhibitor 31 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tubulin inhibitor 31 is a potent tubulin inhibitor with an IC50 value of 4 µM. Tubulin inhibitor 31 shows anti-proliferative activity. Tubulin inhibitor 31 inhibits the HUVEC migration[1].

IC50 & Target

IC50: 4 µM (Tubulin)[1]

体外研究
(In Vitro)

Tubulin inhibitor 31 (compound 4J) (0-100 µM; 72 h) 显示出抗增殖活性,对于 HUVEC、HIG-82 细胞的 IC50 值分别为 0.126、0.39 µM[1]
Tubulin inhibitor 31 (0.012, 0.063 µM; 10 h) 以剂量依赖性方式显着抑制 HUVEC 迁移[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: HUVEC, HIG-82 cells
Concentration: 0-100 µM
Incubation Time: 72 h
Result: Showed anti-proliferative activity with IC50s of 0.126, 0.39 µM for HUVEC, HIG-82 cells.
分子量

329.39

Formula

C22H19NO2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Tubulin inhibitor 31 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tubulin inhibitor 31
目录号:
HY-151996
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