2. Metabolic Enzyme/Protease NF-κB
  3. MALT1
  4. Val-Arg-Pro-DL-Arg-Fluoromethylketone

Val-Arg-Pro-DL-Arg-Fluoromethylketone 

目录号: HY-P4544
产品使用指南

摩尔计算器

Val-Arg-Pro-DL-Arg-Fluoromethylketone 是一种有效的 MALT1 抑制剂。Val-Arg-Pro-DL-Arg-Fluoromethylketone 抑制细胞增殖和迁移。 Val-Arg-Pro-DL-Arg-Fluoromethylketone 具有抗癌活性。

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Custom Peptide Synthesis

Val-Arg-Pro-DL-Arg-Fluoromethylketone Chemical Structure

Val-Arg-Pro-DL-Arg-Fluoromethylketone Chemical Structure

CAS No. : 1926163-57-6

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Val-Arg-Pro-DL-Arg-Fluoromethylketone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. Val-Arg-Pro-DL-Arg-Fluoromethylketone inhibits cell proliferation and migration. Val-Arg-Pro-DL-Arg-Fluoromethylketone shows anticancer activity[1].

IC50 & Target

MALT1[1]
体外研究
(In Vitro)

Val-Arg-Pro-DL-Arg-Fluoromethylketone (75 mol/L; 6, 12, 24, 36, and 48 h) 抑制 OCI-LY10 细胞的增殖和迁移[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Val-Arg-Pro-DL-Arg-Fluoromethylketone 相关抗体:

Cell Proliferation Assay[1]

Cell Line: OCI-LY10 cells
Concentration: 75 mol/L
Incubation Time: 6, 12, 24, 36, and 48 h
Result: Inhibited the proliferation and migration of OCI-LY10 cells.
体内研究
(In Vivo)

Val-Arg-Pro-DL-Arg-Fluoromethylketone (37.5 M*0.2 mL；每隔一天，持续 12 天) 抑制小鼠肿瘤的生长[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 4-6 weeks, 16-20 g, Female BALB/c nude mice (OCI-LY10 cells)[1]
Dosage: 37.5 M*0.2 mL
Administration: Every other day for 12 days
Result: Inhibited the growth of the xenografts and decreased the expression of P65.
分子量

676.78

Formula

C31H49FN10O6
CAS 号
Sequence

Val-Arg-Pro-{DL-Arg}-{Fluoromethylketone}
Sequence Shortening

VRP-{DL-Arg}-{Fluoromethylketone}
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Val-Arg-Pro-DL-Arg-Fluoromethylketone 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Val-Arg-Pro-DL-Arg-Fluoromethylketone1926163-57-6MALT1mucosa associated lymphoid tissue lymphoma translocation gene 1anticancerOCI-LY10 cellsproliferationmigrationP65DLBCLInhibitorinhibitorinhibit

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