1. Anti-infection
  2. RABV
  3. Zamerovimab

Zamerovimab  (Synonyms: CTB011; SYN023)

目录号: HY-P99513

Zamerovimab (CTB011; SYN023) 是一种人源化单克隆抗体混合物,由 CTB011 和 CTB012 组成。Zamerovimab 可以与狂犬病病毒 (RABV) 糖蛋白上的非重叠表位结合,其中 CTB011 与抗原位点III结合。Zamerovimab 可以用于狂犬病研究。

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Zamerovimab Chemical Structure

Zamerovimab Chemical Structure

CAS No. : 2419087-87-7

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规格 是否有货
1 mg
询价
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zamerovimab (CTB011; SYN023) is a mixture of human monoclonal antibodies consisting of CTB011 and CTB012. Zamerovimab binds to non-overlapping epitopes on rabies virus (RABV) glycoprotein, where CTB011 binds to antigenic site III. Zamerovimab can be used in rabies studies[1].

同型

Human IgG1 kappa

推荐同型对照抗体
种属

Humanized

体外研究
(In Vitro)

Zamerovimab (CTB011; SYN023) (0.001-100 μg/mL, 4 h) 在 CVS 感染的 BSR 细胞中,以剂量依赖性方式诱导细胞毒性,促进病毒清除,也表明细胞毒性与表达 G 蛋白的细胞特异性相关,而这些细胞被 CTB011 靶向[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Zamerovimab (CTB011; SYN023) (0.03-1.0 mg/kg,右腓肠肌注射,一次,35 天) 可以以剂量依赖性方式增加感染了狂犬病病毒RABV BD06 的叙利亚仓鼠的存活率,在剂量分别为 0.03、0.1、0.3、1.0 mg/kg 时,存活率分别为 58%,83%,100% 和 100%[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Zamerovimab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Zamerovimab
目录号:
HY-P99513
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