2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. Zilovertamab

Zilovertamab  (Synonyms: UC-961; Cirmtuzumab)

目录号: HY-P99201 纯度: 98.20%
COA

摩尔计算器

Zilovertamab (UC-961) 是一种人源化抗 ROR1 单克隆抗体，可阻断 Wnt5a 诱导的 ROR1 信号通路。

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Zilovertamab Chemical Structure

Zilovertamab Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥3200
In-stock
5 mg   询价  
10 mg   询价  

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Customer Review

Zilovertamab 相关抗体

Top Publications Citing Use of Products

查看 ROR 亚型特异性产品:

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RORγ RORα RORβ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling[1].

体外研究
(In Vitro)

Zilovertamab (25 and 50 µg/mL; 72 h) inhibits high-grade serous ovarian cancer (HGSOC) cell proliferation[1].
Zilovertamab (50 µg/mL; 72 h) down-regulates ROR1 expression levels in CaOV3 at the transcriptional level[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Zilovertamab 相关抗体:

Cell Proliferation Assay[1]

Cell Line: CaOV3, CaOV3CisR, PEO1, and PEO4 cells
Concentration: 25 and 50 µg/mL
Incubation Time: 72 hours
Result: Reduced the proliferation of CaOV3, CaOV3CisR and PEO1.

Western Blot Analysis[1]

Cell Line: CaOV3, CaOV3CisR, PEO1, and PEO4 cells
Concentration: 50 µg/mL
Incubation Time: 72 hours
Result: Down-regulated ROR1 expression levels in CaOV3 at the transcriptional level.
Clinical Trial
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 98.20%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Zilovertamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZilovertamabUC-961 CirmtuzumabUC961UC 961RORRAR-related orphan receptorhumanised monoclonal antibodyWnt5aROR1 signallingCaOV3Inhibitorinhibitorinhibit

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目录号：
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