Car2 - carbonic anhydrase 2 Gene

中文名称：碳酸酐酶 2

种属: Mus musculus

同用名: Ca2; CAII; Car-2; Ltw-5; Lvtw-5

关于 Car2

功能概要

该基因编码的蛋白可启动碳酸盐脱水酶活性。参与二肽跨膜转运的正向调节和细胞内 pH 的调节。作用于多个过程的上游或内部，包括二氧化碳运输； GABAergic 突触传递的正向调节；和细胞 pH 值降低的正向调节。位于胞质溶胶和髓鞘中。以多种结构表达，包括消化系统；脑;心;后肾;和感觉器官。用于研究常染色体隐性骨硬化症 3。该基因的人类直系同源物涉及常染色体隐性骨硬化症 3 和骨硬化症。与人类 CA2（碳酸酐酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables carbonate dehydratase activity. Involved in positive regulation of dipeptide transmembrane transport and regulation of intracellular pH. Acts upstream of or within several processes, including carbon dioxide transport; positive regulation of GABAergic synaptic transmission; and positive regulation of cellular pH reduction. Located in cytosol and myelin sheath. Is expressed in several structures, including alimentary system; brain; heart; metanephros; and sensory organ. Used to study autosomal recessive osteopetrosis 3. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 3 and osteopetrosis. Orthologous to human CA2 (Carbonic Anhydrase 2). [provided by Alliance of Genome Resources, Apr 2022]