1. Gene
  2. NCR3LG1 - natural killer cell cytotoxicity receptor 3 ligand 1 Gene

NCR3LG1 - natural killer cell cytotoxicity receptor 3 ligand 1 Gene

中文名称:自然杀伤细胞细胞毒性受体 3 配体 1

种属: Homo sapiens

同用名: B7H6; B7-H6; DKFZp686O24166

基因 ID: 374383 | 基因类型: protein coding

关于 NCR3LG1

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:17,351,800-17,381,661 (from NCBI)

This gene has 2 transcripts (splice variants), 83 orthologues and 2 paralogues. Broad expression in colon (RPKM 2.1), duodenum (RPKM 1.9) and 21 other tissues.

功能概要

B7H6 属于 B7 家族 (参见 MIM 605402) 并在肿瘤细胞上选择性表达。 B7H6 与 NKp30 (NCR3;MIM 611550) 的相互作用会导致自然杀伤 (NK) 细胞活化和细胞毒性 (Brandt 等人,2009 [PubMed 19528259]) 。[OMIM 提供,2011 年 1 月]

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]

NCR3LG1 基因产物(1)

mRNA Protein Name
NM_001202439.3 NP_001189368.1 natural cytotoxicity triggering receptor 3 ligand 1 precursor

NCR3LG1 蛋白结构

C1-set

C1-set: Immunoglobulin C1-set domain (160 - 239)

Gag_MA

Gag_MA: Matrix protein (MA), p15 (295 - 387)

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  • 454 a.a.
蛋白主名 其他名称

natural cytotoxicity triggering receptor 3 ligand 1

B7 homolog 6

重组 NCR3LG1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7631 B7-H6 Protein, Human (HEK293, His) Q68D85 (D25-S262) ≥95%
HY-P72839 B7-H6 Protein, Human (HEK293, Fc) Q68D85 (M1-S262) ≥95%
HY-P78076 B7-H6 Protein, Human (Biotinylated, HEK293, His-Avi) Q68D85 (D25-S262) ≥95%
HY-P78928 B7-H6 Protein, Human (Biotinylated, HEK293, Fc-Avi) Q68D85 (D25-S262) ≥95%

直系同源

种属 基因名 来源 基因 ID
Felis catus NCR3LG1 VGNC VGNC:81975
Rattus norvegicus NCR3LG1 RGD RGD:1588614
Canis familiaris NCR3LG1 VGNC VGNC:52271
Macaca fascicularis NCR3LG1 NCBI
Others NCR3LG1 NCBI