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基因富集分析

基因富集分析是一种生物信息学方法,用于识别基因集合中富集的功能、通路或生物学特征。通过比较实验中的基因集合与数据库中的已知功能或通路的基因集合,可以发现与实验条件相关的生物学特征。常见的基因富集分析工具包括DAVID、Enrichr、GOseq等。这种分析有助于揭示实验数据中潜在的生物学意义,为基因表达、蛋白组学等高通量实验提供解释和生物学见解。


Gene enrichment analysis is a bioinformatics method used to identify enriched functions, pathways, or biological features in gene sets. By comparing the set of genes in the experiment to sets of genes with known functions or pathways in the database, biological features related to the experimental conditions can be discovered. Common gene enrichment analysis tools include DAVID, Enrichr, GOseq, etc. This analysis helps reveal potential biological meanings in experimental data, providing interpretation and biological insights for high-throughput experiments such as gene expression and proteomics.