2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. RAR/RXR
  4. Retinoic acid

Retinoic acid  (Synonyms: 维生素A酸; Vitamin A acid; all-trans-Retinoic acid; ATRA)

目录号: HY-14649G
产品使用指南

摩尔计算器

Retinoic acid (Vitamin A acid) (GMP) 是 GMP 级别的 Retinoic acid (HY-14649)。GMP 级别的小分子可用做细胞疗法中的辅助试剂。Retinoic acid 是 RAR 核受体的激动剂。

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Retinoic acid Chemical Structure

Retinoic acid Chemical Structure

CAS No. : 302-79-4

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规格 价格 是否有货
10 mg ￥10800
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Retinoic acid 的其他形式现货产品:

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Other Forms of Retinoic acid:

Retinoic acid 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 54 篇科研文献

WB

    Retinoic acid purchased from MCE. Usage Cited in: Oncotarget. 2017 Nov 22;8(65):109135-109150.  [Abstract]

    MCF-7 cells are pretreated with the indicated chemical inhibitors for 30min, followed by 15 min treatment with RA (20 μM) + EPA (80 μM).Cell extracts are prepared and subjected to western blotting analysis.

    Retinoic acid purchased from MCE. Usage Cited in: Oncotarget. 2017 Nov 22;8(65):109135-109150.  [Abstract]

    Cells are treated with RA (20 μM) plus ω-3 PUFAs (80 μM) with or without CQ (5 μM) for 24 h. Cell extracts are prepared and subjected to western blotting analysis.

    Retinoic acid purchased from MCE. Usage Cited in: Oncotarget. 2017 Nov 22;8(65):109135-109150.  [Abstract]

    Cell morphology of MCF-7 treated with RA (20 μM)+ω-3 PUFAs (80 μM) with or without 3-MA (5 mM) for 24h.

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6].

    体外研究
    (In Vitro)

    Retinoic acid (GMP) time- and dose- dependently induces differentiation of EC cells and ES cells into specific cell types[1].
    Retinoic acid (GMP) induces partial differentiation of F9 embryonal carcinoma cells into endoderm cells[2].
    Retinoic acid (GMP) (100 nM; 2-8 d) promotes photoreceptor differentiation in early postnatal retinal cultures[3].
    Retinoic acid (GMP) (0.1 μM; 10-12 d) induces human SH-SY5Y neuroblastoma cells differentiation with long cell processes[4].
    Retinoic acid (GMP) (0-10 μM; 48 h) dose-dependently induces morphologic differentiation of LA-N-1 human neuroblastoma cells[5].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    Retinoic acid 相关抗体:
    体内研究
    (In Vivo)

    Retinoic acid (GMP) (0.3 μM; embryos are immersed in tank water containing retinoic acid) accelerates of rod differentiation is observed following 24 and 48 hours of application in zebrafish[6].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.
    Clinical Trial
    分子量

    300.44

    Formula

    C20H28O2
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Retinoic acid 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Retinoic acid (GMP)302-79-4Vitamin A acid (GMP) all-trans-Retinoic acid (GMP) ATRA (GMP)RAR/RXRRetinoic acid receptorsRetinoid X receptorsGMPdifferentiationECESF9 embryonal carcinoma cellSH-SY5Y neuroblastomaneuroblastomaInhibitorinhibitorinhibit

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