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  2. Saccharides and Glycosides

Saccharides and Glycosides

Saccharide is also called carbohydrate, consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with the empirical formula Cm(H2O)n. The saccharides are divided into four chemical groups: monosaccharides, disaccharides, oligosaccharides, and polysaccharides. Carbohydrates perform numerous roles in living organisms. Polysaccharides serve for the storage of energy (e.g. starch and glycogen) and as structural components. The 5-carbon monosaccharide ribose is an important component of coenzymes (e.g. ATP, FAD and NAD) and the backbone of the genetic molecule known as RNA. The related deoxyribose is a component of DNA. Saccharides and their derivatives include many other important biomolecules that play key roles in the immune system, fertilization, preventing pathogenesis, blood clotting, and development.

A glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body.

Saccharides and Glycosides (593):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1049
    Digoxin 20830-75-5 98.99%
    Digoxin是 Na+/K+-ATPase 的有效抑制剂,临床上用于治疗心律失常和心力衰竭。
    Digoxin
  • HY-N0184
    Glycyrrhizic acid 1405-86-3 >98.0%
    Glycyrrhizic acid 是甘草里面的活性成分三萜皂苷,为 HMGB1 的拮抗剂,具有抗肿瘤、抗糖尿病等功效。
    Glycyrrhizic acid
  • HY-N4000
    Digitonin 11024-24-1
    Digitonin是从洋地黄中提取的糖苷,可通过与胆固醇分子结合来增加细胞膜的通透性,并能抑制肿瘤生长。
    Digitonin
  • HY-13005
    Fagomine 53185-12-9 >98.0%
    Fagomine 是一种温和的糖苷酶 (glycosidase) 抑制剂,Fagomine 作用于 Amyloglucosidase (A.niger),β-Glucosidase (bovine) 和 Isomaltase (yeast),Ki 分别为 4.8 μM,39 μM 和 70 μM。
    Fagomine
  • HY-B0633A
    Hyaluronic acid 9004-61-9
    Hyaluronic acid (来自玉米发酵) 是由二糖的重复单元组成的生物聚合物,应用领域广泛。
    Hyaluronic acid
  • HY-N0109
    Salidroside 10338-51-9 98.50%
    Salidroside 是一种脯氨酰内肽酶 (prolyl endopeptidase) 抑制剂。Salidroside 可通过激活 mTOR 信号缓解肿瘤恶病质小鼠模型中的恶病质症状。Salidroside 还能通过增强 PINK1/Parkin 介导的线粒体自噬来保护多巴胺能神经元。
    Salidroside
  • HY-N0014
    Icariin 489-32-7 98.75%
    Icariin 是一种黄酮醇苷。 Icariin 抑制 PDE5PDE4 活性,IC50 分别为 432 nM 和 73.50 μM。Icariin 也是一种 PPARα 激活剂。
    Icariin
  • HY-N0143
    Phlorizin 60-81-1
    Phlorizin 是一种非选择性的 SGLT 抑制剂,对于 hSGLT1hSGLT2Ki 值分别为 300 和 39 nM。Phlorizin 也是一个 Na+/K+-ATPase 抑制剂。
    Phlorizin
  • HY-B0228
    Adenosine 58-61-7 99.84%
    Adenosine 通过β-N9-糖苷键与核糖分子(呋喃核糖)部分连接的腺嘌呤分子组成的核苷。
    Adenosine
  • HY-N0431
    Astragaloside IV 84687-43-4 >98.0%
    Astragaloside IV 是从黄芪中分到的皂苷类物质,能够抑制 ERK1/2JNK 的激活,在乳腺癌细胞 MDA-MB-231 中,能够下调 (MMP)-2,(MMP)-9 的信号通路。
    Astragaloside IV
  • HY-N0197
    Baicalin 21967-41-9 98.01%
    Baicalin 是一种从 Scutellaria baicalensis 中分离出来的类黄酮糖苷。Baicalin 降低 NF-κB 表达。
    Baicalin
  • HY-B1511
    Cyclic AMP 60-92-4 >98.0%
    Cyclic AMP (cAMP) 是有丝分裂信使,在细胞周期中能够促进 G1 期到 S 期的过程。
    Cyclic AMP
  • HY-N0018
    Daidzin 552-66-9 99.53%
    大豆苷(Daidzin)是一种异黄酮具有抗氧化,抗癌,抗动脉粥样硬化活性。
    Daidzin
  • HY-B1357
    Digitoxin 71-63-6 99.18%
    Digitoxin是有效的 Na+/K+-ATPase抑制剂, EC50 值为0.78 μM。
    Digitoxin
  • HY-N0603
    20(S)-Ginsenoside Rg3 14197-60-5 >98.0%
    20(S)-Ginsenoside Rg3 是红参的主要成分。20(S)-Ginsenoside Rg3 抑制 Na+hKv1.4 通道,IC50 分别为 32.2±4.5 和 32.6±2.2 μM。20(S)-Ginsenoside Rg3 还抑制 NF-κB 活性和 COX-2 表达。
    20(S)-Ginsenoside Rg3
  • HY-B0389
    Dextrose 50-99-7 >98.0%
    Dextrose(D-glucose)是重要的单糖。
    Dextrose
  • HY-N0439
    Asiaticoside 16830-15-2 99.84%
    Asiaticoside 是从积雪草中分到的三萜皂苷化合物,在瘢痕疙瘩成纤维细胞中,通过活化 Smad7,抑制 TGF-βRI 和 TGF-βRII,抑制 TGF-β/Smad 信号通路;Asiaticoside 具有抗氧化、抗炎、抗溃疡等功效。
    Asiaticoside
  • HY-B0089
    Acarbose 56180-94-0 >98.0%
    Acarbose 是α葡萄糖苷酶抑制剂,具有抗糖尿病的作用。
    Acarbose
  • HY-N0148
    Rutin 153-18-4 >98.0%
    Rutin是天然的黄酮苷,具有抗炎,抗氧化、抗过敏、抗病毒等功效。
    Rutin
  • HY-N0527
    Pentagalloylglucose 14937-32-7 99.04%
    Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) 存在于多种植物中,具有重要的药理作用。
    Pentagalloylglucose