2. Epigenetics PI3K/Akt/mTOR Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. AMPK PPAR Glucokinase
  4. Palmitelaidic Acid

Palmitelaidic Acid  (Synonyms: 软脂酸; 9-trans-Hexadecenoic acid; trans-Palmitoleic acid)

目录号: HY-N2341 纯度: ≥99.0%
COA 产品使用指南

摩尔计算器

Palmitelaidic Acid (9-trans-Hexadecenoic acid) 是棕榈油酸 palmitoleic acid 的反式异构体。 棕榈油酸是血清和组织中最丰富的脂肪酸之一。

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Palmitelaidic Acid Chemical Structure

Palmitelaidic Acid Chemical Structure

CAS No. : 10030-73-6

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规格 价格 是否有货 数量
10 mg (393 mM * 100 μL in Ethanol) ￥500
In-stock
25 mg (393 mM * 250 μL in Ethanol) ￥1000
In-stock
50 mg (393 mM * 500 μL in Ethanol) ￥1600
In-stock

* Please select Quantity before adding items.

Customer Review

Other Forms of Palmitelaidic Acid:

Palmitelaidic Acid 相关抗体

Top Publications Citing Use of Products

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.

IC50 & Target

AMPK

 

PPARα

 

Glucokinase

 

体外研究
(In Vitro)

The monounsaturated fatty acid palmitoleate (palmitoleic acid) is one of the most abundant fatty acids in serum and tissues, particularly adipose tissue and liver. Its endogenous production by stearoyl-CoA desaturase 1 gives rise to its cis isoform, cis-palmitoleate. Palmitoleic acid has been correlated with multiple cardiometabolic risk factors, including high blood pressure, total cholesterol, TGs, apoA-I, apoB, and endothelial dysfunction[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Palmitelaidic Acid 相关抗体:
体内研究
(In Vivo)

Palmitoleic acid promotes a faster uptake of glucose in the body, associated with higher insulin concentration. Palmitoleic acid increases the phosphorylation of AMPK, up-regulates glucokinase and down-regulates SREBP-1. Regarding AMPK downstream, palmitoleic acid increases the production of FGF-21 and stimulates the expression of PPARα[2]. Palmitoleic acid reduces body weight increase, ameliorates the development of hyperglycemia and hypertriglyceridemia, and improves insulin sensitivity. Furthermore, palmitoleic acid down-regulates mRNA expressions of proinflammatory adipocytokine genes (TNFα and resistin) in white adipose tissue and lipogenic genes (SREBP-1, FAS, and SCD-1) in liver[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

254.41

Formula

C16H30O2
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

棕榈酸酯；软脂酸
结构分类
初始来源

 beef samples
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
溶解性数据
In Vitro: 

Ethanol 中的溶解度 : 100 mg/mL (393.07 mM; 超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥99.0%

COA (182 KB)

产品使用指南 (1538 KB)
参考文献
Animal Administration
[2]

Mice: Male C57BL/6J wild type and PPARα-KO mice are fed a high-fat diet or a standard diet for 12 weeks. In the last two weeks, the HF-fed mice are treated daily with oleic acid (300 mg/kg of body weight) or palmitoleic acid (00 mg/kg of body weight) by oral gavage. After 12 weeks, the mice are fasted for 6 h, injected with insulin or PBS vehicle. Blood and liver samples are collected and stored for the further analysis of RNA and protein expression[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Palmitelaidic Acid 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 3.9307 mL 19.6533 mL 39.3066 mL 98.2666 mL
5 mM 0.7861 mL 3.9307 mL 7.8613 mL 19.6533 mL
10 mM 0.3931 mL 1.9653 mL 3.9307 mL 9.8267 mL
15 mM 0.2620 mL 1.3102 mL 2.6204 mL 6.5511 mL
20 mM 0.1965 mL 0.9827 mL 1.9653 mL 4.9133 mL
25 mM 0.1572 mL 0.7861 mL 1.5723 mL 3.9307 mL
30 mM 0.1310 mL 0.6551 mL 1.3102 mL 3.2756 mL
40 mM 0.0983 mL 0.4913 mL 0.9827 mL 2.4567 mL
50 mM 0.0786 mL 0.3931 mL 0.7861 mL 1.9653 mL
60 mM 0.0655 mL 0.3276 mL 0.6551 mL 1.6378 mL
80 mM 0.0491 mL 0.2457 mL 0.4913 mL 1.2283 mL
100 mM 0.0393 mL 0.1965 mL 0.3931 mL 0.9827 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Palmitelaidic Acid10030-73-69-trans-Hexadecenoic acid trans-Palmitoleic acid棕榈酸酯软脂酸AMPKPPARGlucokinaseAMP-activated protein kinasePeroxisome proliferator-activated receptorsHexokinase IVHexokinase DInhibitorinhibitorinhibit

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