2. Signaling Pathways
  3. Epigenetics
    Metabolic Enzyme/Protease
  4. S-adenosylhomocysteine hydrolase (SAHH)

S-adenosylhomocysteine hydrolase (SAHH) 

SAHH

S-adenosylhomocysteine hydrolase (SAHH) is an NAD+ dependent tetrameric enzyme that catalyzes the hydrolysis of S-adenosylhomocysteine to adenosine and homocystein, participates in the methionine, transsulfurization and transmethylation metabolic pathways, regulates the intracellular levels of homocysteine ​​and adenosine, and thus affecting various aspects of biological metabolism. S-adenosylhomocysteine hydrolase regulates the gene expression and cell growth. S-adenosylhomocysteine hydrolase is related to virus infection, parasite growth like Leishmania, and hyperhomocysteinemia such as atherosclerotic vascular disease and thromboembolic disease[1].

S-adenosylhomocysteine hydrolase (SAHH) 相关产品 (5):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-12186
    3-Deazaneplanocin A hydrochloride

    3-去氮腺嘌呤A盐酸盐

    		Inhibitor 99.98%
    3-Deazaneplanocin A hydrochloride (DZNep hydrochloride) 是一种有效的组蛋白甲基转移酶 (EZH2) 抑制剂。3-Deazaneplanocin A hydrochloride 是一种有效的 S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。3-Deazaneplanocin A hydrochloride 还具有抗正痘病毒 (orthopoxvirus) 和抗天花病毒活性。
    3-Deazaneplanocin A hydrochloride
  • HY-W013332
    3-Deazaadenosine

    3-脱氮腺苷

    		Inhibitor ≥99.0%
    3-Deazaadenosine 是一种 S-腺苷高半胱氨酸水解酶 (S-adenosylhomocysteine hydrolase) 抑制剂，Ki 值为 3.9 μM；3-Deazaadenosine 具有抗炎、抗增殖、抗 HIV 等活性。
    3-Deazaadenosine
  • HY-W013332A
    3-Deazaadenosine hydrochloride Inhibitor 99.67%
    3-Deazaadenosine hydrochloride 是一种 S-腺苷高半胱氨酸水解酶 (S-adenosylhomocysteine hydrolase) 抑制剂，Ki 值为 3.9 μM。3-Deazaadenosine (hydrochloride) 具有抗炎、抗增殖、抗 HIV 等活性。
    3-Deazaadenosine hydrochloride
  • HY-112639
    Aristeromycin Inhibitor 99.34%
    Aristeromycin，腺苷类似物，是一种抗生素和有效的S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。
    Aristeromycin
  • HY-W002968
    SAHH-IN-1 Inhibitor
    SAHH-IN-1 是一种 S-腺苷同型半胱氨酸水解酶 (SAHH) 抑制剂，其 IC50 为 814 nM。SAHH-IN-1 可用于研究年龄相关性退行性疾病 (如阿尔茨海默病)。
    SAHH-IN-1
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