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  3. AP-1/NF-κB activation inhibitor 1

AP-1/NF-κB activation inhibitor 1 

目录号: HY-133987
产品使用指南

AP-1/NF-κB activation inhibitor 1 是一种有效的 AP-1 NF-κB 介导的转录激活抑制剂(IC50=1 μM),不阻断 β-actin 启动子驱动的基础转录。AP-1/NF-κB activation inhibitor 1 对受刺激细胞产生IL-2和IL-8水平有相似的抑制作用。

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AP-1/NF-κB activation inhibitor 1 Chemical Structure

AP-1/NF-κB activation inhibitor 1 Chemical Structure

CAS No. : 188936-12-1

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Description

AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1].

Molecular Weight

344.25

Formula

C₁₃H₁₁F₃N₄O₄

CAS No.

188936-12-1

SMILES

O=C(C1=CN=C(C(F)(F)F)N=C1NN2C(C(C)=CC2=O)=O)OCC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

AP-1/NF-κB activation inhibitor 1NF-κBNuclear factor-κBNuclear factor-kappaBtranscriptionalactivationstimulatedIL-2IL-8Inhibitorinhibitorinhibit

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产品名称:
AP-1/NF-κB activation inhibitor 1
目录号:
HY-133987
需求量: