2. Apoptosis Immunology/Inflammation
  3. Apoptosis Interleukin Related
  4. Apoptosis inducer 42

Apoptosis inducer 42 是一种凋亡 (apoptosis) 诱导剂。Apoptosis inducer 42 可激活晚期凋亡并抑制 IL-6 的分泌。Apoptosis inducer 42 对癌细胞具有高细胞毒性。Apoptosis inducer 42 可用于癌症研究, 如结肠癌。

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Apoptosis inducer 42

Apoptosis inducer 42 Chemical Structure

CAS No. : 66685-93-6

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Apoptosis inducer 42 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Apoptosis inducer 42 is an apoptosis inducer. Apoptosis inducer 42 activates late apoptosis and inhibits IL-6 secretion. Apoptosis inducer 42 shows high cytotoxicity towards cancer cells. Apoptosis inducer 42 can be used for cancer research, such as colon cancer[1].

IC50 & Target[1]

IL-6

 

体外研究
(In Vitro)

Apoptosis inducer 42 (Compound 11) 可抑制 SW480、SW620、PC3f、HCT116 和 HaCaT 细胞的生长，其 IC50 值分别为 5.1、6.3、6.0、4.4 和 14.2 μM[1]。
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) 可减少 SW480、SW620、PC3f 和 HCT116 细胞中的活细胞数量[1]。
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) 可激活 SW480、SW620、PC3f 和 HCT116 细胞的晚期凋亡，并抑制 IL-6 的分泌[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis inducer 42 相关抗体:

Apoptosis Analysis[1]

Cell Line: SW480, SW620, PC3f and HCT116 cells
Concentration: 5.1 μM in SW480, 6.3 μM in SW620, 6.0 μM in PC3f, 4.4 μM in HCT116 cells
Incubation Time: 72 h
Result: Activated >80% late apoptosis.
分子量

224.26

Formula

C11H13OPS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Apoptosis inducer 42 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptosis inducer 4266685-93-6Apoptosis inducer42Apoptosis inducer-42ApoptosisInterleukin RelatedILIL-6SW480SW620PC3fHCT116Inhibitorinhibitorinhibit

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Apoptosis inducer 42
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