1. Biology Dictionary
  2. Genetic Interference Approach

Genetic Interference Approach遗传干扰

释义:

This term refers to methods that aim at interfering with the activity of a specific gene by altering the gene regulatory or coding sequences. This goal can be achieved either by a classical genetic approach (random mutagenesis followed by phenotype characterization and genetic mapping) or by a reverse genetics approach where a gene of interest is modified by directed mutagenesis.

该术语指的是通过改变基因的调控序列或编码序列来干扰特定基因活性的方法。此目标可以通过经典的遗传方法 (随机突变及表型特征描述与遗传图谱分析) 或者通过反向遗传学方法 (通过定向突变修改感兴趣的基因) 实现。

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