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Boc5 是一种非肽类胰高血糖素样肽-1受体激动剂。Boc5 在糖尿病小鼠中引起持续的血糖控制和体重减轻。Boc5 可用于糖尿病研究。

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Boc5 Chemical Structure

Boc5 Chemical Structure

CAS No. : 917569-14-3

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Boc5 is a non-peptidic glucagon-like peptide-1 receptor agonist. Boc5 causes sustained glycemic control and weight loss in diabetic mice. Boc5 can be used in research of diabetic[1][2].

体内研究
(In Vivo)

Boc5 (0.1-3 mg/只小鼠; i.p.; 患有糖尿病的 db/db 小鼠) 具有抗糖尿病活性,并能以剂量依赖性方式改善血糖控制[1]
Boc5 (0.1-3 mg/只小鼠; i.p.; 患有糖尿病的 db/db 小鼠) 具有抗肥胖活性并可减轻糖尿病小鼠的体重[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: diabetic db/db mice[1]
Dosage: 0.1-3 mg/mice
Administration: Intraperitoneal injection
Result: Had a dose-dependent fall of up to 14.6 mM glucose, and an ED50 of 0.87 mg/day.
Animal Model: diabetic db/db mice[1]
Dosage: 0.1-3 mg/mice
Administration: Intraperitoneal injection
Result: Decreased fat as a percent of total body mass in a dose-dependent manner.
分子量

1077.14

Formula

C54H52N4O16S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Boc5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-135195
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