1. Saccharides and Glycosides
    Terpenoids and Glycosides
  2. Cimicifugoside

Cimicifugoside 

目录号: HY-N7119
产品使用指南

Cimicifugoside 是一种从升麻单胞菌 Cimicifuga simplex 中提取的三萜类化合物,是一种新型特异性核苷转运 (nucleoside transport) 抑制剂,协同增强甲氨蝶呤细胞毒性作用。Cimicifugoside 具有免疫抑制活性,其优先针对 B 细胞功能,需要较大剂量来抑制 T 细胞功能。

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Cimicifugoside Chemical Structure

Cimicifugoside Chemical Structure

CAS No. : 66176-93-0

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生物活性

Cimicifugoside, a triterpenoid isolated from Cimicifuga simplex, is a novel specific nucleoside transport inhibitor that displays synergistic potentiation of methotrexate cytotoxicity[1]. Cimicifugoside shows immunosuppressive activity, which is preferentially directed toward B-cell function with larger doses being required for suppression of T-cell function[2].

IC50 & Target

Nucleoside transport[1]

分子量

674.82

Formula

C₃₇H₅₄O₁₁

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

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Cimicifugoside
目录号:
HY-N7119
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