1. Metabolic Enzyme/Protease Anti-infection
  2. Glycosidase Bacterial
  3. CKD-711

CKD-711 是一种具有口服活性的氨基寡糖 α-葡萄糖苷酶 (α-glucosidase) 抑制剂,其 IC50 值为 78 μg/mL。CKD-711 对猪肠道麦芽糖酶和蔗糖酶也有抑制作用,IC50 值为 2.5 和 0.5 μg/mL。CKD-711 对土生丛毛单胞菌 (Comamonas terrigena) 表现出选择性抗菌活性。CKD-711 可用于感染和代谢疾病的研究,如糖尿病。

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CKD-711

CKD-711 Chemical Structure

CAS No. : 445010-62-8

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CKD-711 is an orally active aminooligosaccharide α-glucosidase inhibitor with an IC50 of 78 μg/mL. CKD-711 also inhibits porcine intestinal maltase and sucrose with IC50 values of 2.5 and 0.5 μg/mL. CKD-711 shows selective antibacterial activity against Comamonas terrigena. CKD-711 can be used for the researches of infection and metabolic disease, such as diabetes[1].

IC50 & Target[1]

α‑glucosidase

78 μg/mL (IC50)

体内研究
(In Vivo)

CKD-711 (口服) 可降低喂食淀粉和蔗糖餐的大鼠的餐后血糖升高,其 EC50 值分别为 3.07 mg/kg 和 1.15 mg/kg[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

677.60

Formula

C25H43NO20

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CKD-711
目录号:
HY-105291
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