1. Immunology/Inflammation Anti-infection Apoptosis
  2. Thrombopoietin Receptor Bacterial Apoptosis
  3. Eltrombopag-13C4

Eltrombopag-13C4  (Synonyms: SB-497115-13C4)

目录号: HY-15306S 纯度: ≥97.0%
COA 产品使用指南

Eltrombopag-13C4 (SB-497115-13C4) 带有 13C 标记的 Z-Eltrombopag。Z-Eltrombopag 是一种具有口服活性的 thrombopoietin-receptor 非肽激动剂,可促血小板的活性,用于研究慢性免疫性血小板减少症。Eltrombopag 对多药耐药的金黄色葡萄球菌 (Staphylococcus aureus) 也有很强的抑制作用,还可诱导肝癌细胞凋亡 (apoptosis)。

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Eltrombopag-<sup>13</sup>C<sub>4</sub> Chemical Structure

Eltrombopag-13C4 Chemical Structure

CAS No. : 1217230-31-3

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eltrombopag-13C4 (SB-497115-13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells[1][2][3][4][5].

IC50 & Target

Thrombopoietin Receptor, Staphylococcus aureus, Apoptosis[1][3][5]

分子量

446.44

Formula

C2113C4H22N4O4

CAS 号
性状

固体

颜色

Light yellow to orange

中文名称

艾曲波帕 13C4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥97.0%

参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Eltrombopag-13C4
目录号:
HY-15306S
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