1. Membrane Transporter/Ion Channel
  2. P-glycoprotein
  3. Epoxylathyrol

Epoxylathyrol  (Synonyms: 环氧续随子醇)

目录号: HY-N0425
产品使用指南

Epoxylathyrol 是从大戟 (Euphorbia boetica) 分离出来的环氧乙氧基醚衍生物。Epoxylathyrol 是一种 P-糖蛋白 (P-gp) 抑制剂,也是 P-gp 介导的多药耐药性 (MDR) 逆转剂。

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Epoxylathyrol Chemical Structure

Epoxylathyrol Chemical Structure

CAS No. : 28649-60-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser[1][2].

体外研究
(In Vitro)

Epoxylathyrol has no significant antiproliferative activity in EPG85-257P (parental; IC50>100 uM), EPG85-257RNOV (multidrug resistance [MDR] phenotype; IC50>100 uM), and EPG85-257RDB (multidrug resistance [MDR] phenotype; IC50=70.53 uM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

350.45

Formula

C20H30O5

CAS 号
中文名称

环氧续随子醇

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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