2. Gene
  3. MTOR - mechanistic target of rapamycin kinase Gene

MTOR - mechanistic target of rapamycin kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：雷帕霉素激酶的机制靶点

种属: Sus scrofa

同用名: FRAP1

基因 ID: 100127359 | 基因类型: protein coding

关于 MTOR

Primary_assembly 6: 71,286,989-71,412,888 reverse strand.Sscrofa11.1:CM000817.5

This gene has 3 transcripts (splice variants), 217 orthologues and 5 paralogues. Ubiquitous expression in spleen (RPKM 8.9), lung (RPKM 8.2) and 8 other tissues.

MTOR 基因产物(1)

mRNA Protein Name
XM_003127584.6 XP_003127632.3 serine/threonine-protein kinase mTOR

MTOR 蛋白结构

TEL1

TEL1: COG5032 (367 - 2547)

HEAT

HEAT: sd00044 (654 - 680)

HEAT

HEAT: sd00044 (690 - 720)

HEAT

HEAT: sd00044 (728 - 758)

HEAT

HEAT: sd00044 (771 - 804)

HEAT

HEAT: sd00044 (816 - 846)

HEAT

HEAT: sd00044 (954 - 980)

HEAT

HEAT: sd00044 (992 - 1020)

HEAT

HEAT: sd00044 (1032 - 1061)

HEAT

HEAT: sd00044 (1072 - 1098)

HEAT

HEAT: sd00044 (1110 - 1141)

  • 0
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  • 2000
  • 2400
  • 2548 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase mTOR

FK506 binding protein 12-rapamycin associated protein 1

相关产品

Approval
生物活性分子 (7)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10219 Rapamycin Inhibitor 99.94% 是
HY-10218 Everolimus Inhibitor 99.68% 是
HY-50910 Temsirolimus Inhibitor 99.56% 是
HY-N0486 L-Leucine Activator 99.79% 否
HY-N0281 Daphnetin Inhibitor 99.86% 否
HY-B1232A Metyrapone Tartrate Modulator / 否
HY-B0725A Doxepin / 否
Clinical Phase
生物活性分子 (29)
目录号 产品名 作用方式
纯度 Phase
HY-10219G Rapamycin (GMP) Inhibitor / Phase 4
HY-50673 Dactolisib Inhibitor 99.94% Phase 3
HY-50908 Ridaforolimus Inhibitor 98.81% Phase 3
HY-15174 Dactolisib Tosylate Inhibitor 99.87% Phase 3
HY-13328 Sapanisertib Inhibitor 99.66% Phase 2
HY-139609 Camonsertib Inhibitor 99.75% Phase 2
HY-N0112 Dihydromyricetin Inhibitor 98.10% Phase 2
HY-114384 NV-5138 Activator ≥98.0% Phase 2
HY-15247 Vistusertib Inhibitor 98.21% Phase 2
HY-15177 PF-04691502 Inhibitor 99.91% Phase 2
HY-12513 Samotolisib Inhibitor 99.42% Phase 2
HY-15900 Voxtalisib Inhibitor 98.81% Phase 2
HY-16962 CC-115 Inhibitor 98.04% Phase 2
HY-12868 Bimiralisib Inhibitor 99.80% Phase 2
HY-114384B NV-5138 hydrochloride Activator ≥98.0% Phase 2
HY-13246 Apitolisib Inhibitor 99.65% Phase 2
HY-13334 BGT226 maleate Inhibitor 99.87% Phase 2
HY-16956 Onatasertib Inhibitor ≥97.0% Phase 2
HY-16962A CC-115 hydrochloride Inhibitor 98.23% Phase 2
HY-13334A BGT226 Inhibitor 99.51% Phase 2
HY-13691 MKC-1 Inhibitor 99.23% Phase 2
HY-10422 AZD-8055 Inhibitor 99.60% Phase 1
HY-10297 Omipalisib Inhibitor 99.93% Phase 1
HY-132168 RMC-5552 Inhibitor 98.10% Phase 1
HY-10423 OSI-027 Inhibitor 99.40% Phase 1
HY-16585 VS-5584 Inhibitor 99.14% Phase 1
HY-12036 GSK1059615 Inhibitor ≥99.0% Phase 1
HY-14581 Palomid 529 Inhibitor 99.47% Phase 1
HY-15248 GDC-0349 Inhibitor 97.05% Phase 1
Pre-clinical Phase
生物活性分子 (154)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-B0795 MHY1485 Activator 99.86% 否
HY-13003 Torin 1 Inhibitor 98.95% 否
HY-N0109 Salidroside Activator 99.79% 否
HY-13002 Torin 2 Inhibitor 99.98% 否
HY-U00434 3BDO Activator 99.91% 否
HY-122022 JR-AB2-011 Inhibitor 98.53% 否
HY-10115 PI-103 Inhibitor 98.93% 否
HY-10474 Torkinib Inhibitor 98.37% 否
HY-111373 RapaLink-1 Inhibitor 98.46% 否
HY-124798 Rheb inhibitor NR1 Inhibitor 99.46% 否
HY-100542 D-α-Hydroxyglutaric acid disodium Inhibitor ≥98.0% 否
HY-50710 KU-0063794 Inhibitor 99.55% 否
HY-124719 hSMG-1 inhibitor 11j Inhibitor 99.81% 否
HY-N0189 Aloe emodin Inhibitor 98.32% 否
HY-N0047 Polyphyllin I Inhibitor 99.61% 否
HY-10044 WYE-132 Inhibitor 99.40% 否
HY-10372 PP121 Inhibitor 98.67% 否
HY-10683 PKI-402 Inhibitor 98.43% 否
HY-124760 hSMG-1 inhibitor 11e Inhibitor 99.18% 否
HY-100222 CZ415 Inhibitor 98.74% 否
HY-W016412 Coenzyme Q0 Inhibitor ≥99.0% 否
HY-107365 PQR530 Inhibitor 99.98% 否
HY-10219S Rapamycin-d3 Inhibitor 95.48% 否
HY-134904 RMC-6272 Inhibitor 95.54% 否
HY-109046 Tulrampator 99.07% 否
HY-18353 mTOR inhibitor-3 Inhibitor 99.08% 否
HY-12034 WYE-354 Inhibitor 98.04% 否
HY-10115A PI-103 Hydrochloride Inhibitor 98.00% 否
HY-115449 Chromeceptin p53 Inhibitor 99.91% 否
HY-13431 KU-0060648 Inhibitor 99.39% 否
HY-146751 PI3K/Akt/mTOR-IN-2 Inhibitor 99.86% 否
HY-N0656A (+)-Usnic acid Inhibitor ≥98.0% 否
HY-12763 GNE-317 Inhibitor 99.14% 否
HY-114414 HDACs/mTOR Inhibitor 1 Inhibitor 98.21% 否
HY-15272 WAY-600 Inhibitor 99.75% 否
HY-N0486S9 L-Leucine-d3 Activator ≥98.0% 否
HY-N0107 Cyclovirobuxine D Inhibitor ≥98.0% 否
HY-100026 PQR620 Inhibitor 98.05% 否
HY-112914 mTOR inhibitor-1 Inhibitor 99.50% 否
HY-137175 TMBIM6 antagonist-1 Antagonist 99.60% 否
HY-W058849 MT 63-78 Inhibitor 98.50% 否
HY-N2217 Rotundic acid Inhibitor 99.41% 否
HY-15521 ETP-46464 Inhibitor 99.55% 否
HY-110109 ETP-45658 Inhibitor 98.05% 否
HY-111508 PI3K/mTOR Inhibitor-2 Inhibitor 98.25% 否
HY-N0486S3 L-Leucine-15N Activator ≥98.0% 否
HY-100470 NSC781406 Inhibitor 99.91% 否
HY-100398 PF-04979064 Inhibitor 99.83% 否
HY-N0486S1 L-Leucine-13C Activator ≥98.00% 否
HY-136660 PQR626 Inhibitor 98.05% 否
HY-11080 PKI-179 Inhibitor ≥98.0% 否
HY-128333 PI3K/mTOR Inhibitor-4 Inhibitor 97.00% 否
HY-N0486S L-Leucine-d10 Activator ≥98.0% 否
HY-15271 WYE-687 Inhibitor 98.10% 否
HY-122665A HTH-01-091 TFA Inhibitor 98.01% 否
HY-126077 MTI-31 Inhibitor 99.94% 否
HY-N0486S8 L-Leucine-13C6,15N Activator ≥99.0% 否
HY-N0486S12 L-Leucine-d2 Activator ≥99.0% 否
HY-11080A PKI-179 hydrochloride Inhibitor 98.11% 否
HY-N6950 Hederacolchiside A1 Modulator 99.69% 否
HY-141805 MHY-1685 Inhibitor 99.97% 否
HY-10811 GNE-493 Inhibitor 98.33% 否
HY-131344 mTOR inhibitor-8 Inhibitor 98.04% 否
HY-137315 TML-6 Inhibitor 99.01% 否
HY-145931 CC214-2 Inhibitor 98.41% 否
HY-N6843 Arnicolide D Inhibitor 99.20% 否
HY-N0486S15 L-Leucine-13C6 ≥98.0% 否
HY-11042 GNE-477 Inhibitor 98.70% 否
HY-13806 XL388 Inhibitor 99.25% 否
HY-10812 GNE-490 Inhibitor 96.29% 否
HY-124036 DS-7423 Inhibitor 99.75% 否
HY-114267 Cbz-B3A Inhibitor ≥98.0% 否
HY-153120A PI3K/mTOR Inhibitor-13 sodium Inhibitor 98.13% 否
HY-N4315 Pomiferin Inhibitor 97.36% 否
HY-122665 HTH-01-091 Inhibitor / 否
HY-125927 8-Aminoadenosine Inhibitor / 否
HY-118717 mTOR inhibitor WYE-28 Inhibitor 99.75% 否
HY-134903 (32-Carbonyl)-RMC-5552 Inhibitor 95.04% 否
HY-143510 RMC-4627 / 否
HY-151622 PI3K/mTOR Inhibitor-11 Inhibitor 98.74% 否
HY-151137 HSP90/mTOR-IN-1 Inhibitor / 否
HY-139832 MCX 28 Inhibitor / 否
HY-N3628 Coronarin A Inhibitor / 否
HY-128027 eCF309 Inhibitor / 否
HY-147913 PI3K/Akt/mTOR-IN-3 Inhibitor / 否
HY-155066 FD274 Inhibitor / 否
HY-144687 ATM Inhibitor-4 Inhibitor / 否
HY-146016 PI3K/mTOR Inhibitor-5 Inhibitor / 否
HY-N0486S10 L-Leucine-18O2 Activator / 否
HY-154910 CC214-1 Inhibitor / 否
HY-B1787 Sulindac sulfone Inhibitor / 否
HY-N0486S6 L-Leucine-2-13C,15N Activator / 否
HY-150061 NVP-BBD130 Inhibitor / 否
HY-155376 mTOR inhibitor-14 Inhibitor / 否
HY-N10754 Aschantin Inhibitor / 否
HY-N2517 Dihydroevocarpine Inhibitor 99.62% 否
HY-15281 QL-IX-55 Inhibitor / 否
HY-141476 PI3K/mTOR Inhibitor-3 Inhibitor / 否
HY-157169 IBL-302 Inhibitor / 否
HY-N0486S13 L-Leucine-15N,d10 / 否
HY-101776 Desmethyl-VS-5584 Inhibitor / 否
HY-141701 mTOR/HDAC-IN-1 Inhibitor / 否
HY-113038 D-α-Hydroxyglutaric acid Inhibitor / 否
HY-137315S TML-6-d3 / 否
HY-N1050 Zederone Inhibitor / 否
HY-12652 AZD3147 Inhibitor / 否
HY-15271A WYE-687 dihydrochloride Inhibitor ≥98.0% 否
HY-N0486S4 L-Leucine-d7 Activator / 否
HY-154958 mTOR inhibitor-12 Inhibitor / 否
HY-P5984 Thioether-cyclized helix B peptide, CHBP Inhibitor / 否
HY-147285 PI3K/mTOR Inhibitor-9 Inhibitor / 否
HY-N0486S2 Leucine-13C6 Activator ≥98.0% 否
HY-15269 PP30 Inhibitor / 否
HY-118704 P-2281 Inhibitor / 否
HY-147614 PI3K/mTOR Inhibitor-7 Inhibitor / 否
HY-154957 mTOR inhibitor-11 Inhibitor / 否
HY-N0486S7 L-Leucine-1-13C,15N Activator ≥98.0% 否
HY-10218S Everolimus-d4 Inhibitor / 否
HY-N0486S11 L-Leucine-d1 Activator / 否
HY-137996 Dehydrovomifoliol Inhibitor / 否
HY-115869 RMC-4529 Inhibitor / 否
HY-127067 Yuanhuadin Inhibitor / 否
HY-156027 SIRT6-IN-3 Inhibitor / 否
HY-N5136 25(R,S)-Ruscogenin Inhibitor 99.84% 否
HY-146200 PI3K/mTOR Inhibitor-8 Inhibitor / 否
HY-151915 ATR-IN-20 Inhibitor / 否
HY-103438 BIBU1361 / 否
HY-N1244 Sarmentosin Inhibitor / 否
HY-147613 PI3K/mTOR Inhibitor-6 Inhibitor / 否
HY-156432 ALK-IN-26 Inhibitor / 否
HY-156445 PI3K/mTOR Inhibitor-14 Inhibitor / 否
HY-147966 HDAC-IN-43 Inhibitor / 否
HY-144295 PI3Kα-IN-5 Inhibitor / 否
HY-144449 mTOR/HDAC6-IN-1 Inhibitor / 否
HY-121726 3HOI-BA-01 Inhibitor / 否
HY-144686 ATM Inhibitor-3 Inhibitor / 否
HY-152238 PI3K/mTOR Inhibitor-12 Inhibitor / 否
HY-P5984A Thioether-cyclized helix B peptide, CHBP TFA Inhibitor / 否
HY-155721 22-(4′-py)-JA Inhibitor / 否
HY-N1338 Royleanone Inhibitor / 否
HY-N0486S5 L-Leucine-2-13C Activator / 否
HY-147284 PI3K-IN-37 Inhibitor / 否
HY-123849 SN32976 Inhibitor / 否
HY-153120 PI3K/mTOR Inhibitor-13 Inhibitor / 否
HY-10620 PI3K-IN-22 Inhibitor / 否
HY-155211 mTOR inhibitor-13 Inhibitor / 否
HY-155475 mTORC1-IN-2 Inhibitor / 否
HY-W592871 10-Hydroxy-2-decenoic acid / 否
HY-157167 mTORC1-IN-1 / 否
HY-111065 OXA-01 Inhibitor / 否
HY-112602 PI3K/mTOR Inhibitor-1 Inhibitor / 否
HY-111370 mTOR inhibitor-2 Inhibitor / 否
HY-107363 FT-1518 Inhibitor 98.14% 否
HY-U00326 PI3Kα/mTOR-IN-1 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens MTOR NCBI NCBI:2475