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  2. Relb - RELB proto-oncogene, NF-kB subunit Gene

Relb - RELB proto-oncogene, NF-kB subunit Gene

中文名称:RELB 原癌基因,NF-kB 亚单位

种属: Rattus norvegicus

基因 ID: 100360982 | 基因类型: protein coding

关于 Relb

Primary_assembly 1: 79,257,725-79,285,507 reverse strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 195 orthologues, 4 paralogues and is associated with 13 phenotypes. Biased expression in Spleen (RPKM 67.), Thymus (RPKM 49.5) and 9 other tissues.


该基因编码的蛋白可启动 DNA 结合活性。参与细胞对渗透压的反应。位于核内。用于研究肾脏疾病;肌肉萎缩;和输尿管梗阻。糖尿病前期综合征的生物标志物。该基因与乳腺癌和免疫缺陷 53 相关的人类直向同源基因。与人类 RelB 直向同源基因(RELB 原癌基因,NF-kB 亚基)。 [由基因组资源联盟提供,2022 年 4 月]

Enables DNA binding activity. Involved in cellular response to osmotic stress. Located in nucleus. Used to study kidney disease; muscular atrophy; and ureteral obstruction. Biomarker of prediabetes syndrome. Human ortholog(s) of this gene implicated in breast Cancer and immunodeficiency 53. Orthologous to human RelB (RelB proto-oncogene, NF-kB subunit). [provided by Alliance of Genome Resources, Apr 2022]

Relb 基因产物(6)

mRNA Protein Name
XM_006228503.4 XP_006228565.1 transcription factor RelB isoform X2
XM_017590004.2 XP_017445493.1 transcription factor RelB isoform X4
XM_008759054.3 XP_008757276.1 transcription factor RelB isoform X5
XM_017590005.2 XP_017445494.1 transcription factor RelB isoform X4
XM_017590003.2 XP_017445492.1 transcription factor RelB isoform X3
XM_006228502.4 XP_006228564.1 transcription factor RelB isoform X1

Relb 蛋白结构


RelB_leu_zip: pfam16180 (0 - 76)


RHD-n_RelB: cd07886 (103 - 274)


RHD_dimer: pfam16179 (282 - 378)


RelB_transactiv: cl24684 (381 - 558)

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  • 559 a.a.
蛋白主名 其他名称

transcription factor RelB

avian reticuloendotheliosis viral (v-rel) oncogene related B

v-rel avian reticuloendotheliosis viral oncogene homolog B

v-rel reticuloendotheliosis viral oncogene homolog B


种属 基因名 来源 基因 ID
Homo sapiens Relb NCBI NCBI:5971